Traditional Culture Encyclopedia - Almanac inquiry - What are the types of sulfonamides?
What are the types of sulfonamides?
(1) sulfathiazole
It has strong antibacterial ability. Acetylates are widely used in clinic because of their low solubility, many side effects and rapid excretion.
(2) sulfadiazine
Strong antibacterial ability, slow excretion, high effective concentration in blood, long maintenance time, easy to penetrate into cerebrospinal fluid, suitable for meningitis and other diseases, but due to low solubility, attention should be paid to kidney damage.
(3) sulfamethazine
The antibacterial effect and curative effect are slightly worse than sulfadiazine, but it has inhibitory effect on some rickettsia and protozoa (such as coccidia) and has little damage to the kidney. It can maintain the effective blood concentration in livestock for 24 hours.
(4) sulfamethoxazine
Also known as long-acting sulfanilamide, it is used once a day, with good antibacterial effect and curative effect, but with great side effects.
(5) sulfadiazine
About 30% ~ 50% is absorbed after oral administration, but the effective concentration is not reached, and the intestinal concentration is high.
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