History of pharmacology of traditional Chinese medicine

The development of pharmacology of ephedra began with Mr. Chen's study on the adrenergic effects of ephedrine in the 1920s. Ephedrine was extracted from ephedra sinica and found to have sympathetic effect. In 1970s, Professor Zhou, a Chinese pharmacologist, put forward the slogan of "marching towards the pharmacology of integrated traditional Chinese and western medicine", calling for the establishment of the pharmacology of integrated traditional Chinese and western medicine, and pointed out that it is necessary to study and clarify the pharmacological effects of traditional Chinese medicine from the perspective of traditional Chinese medicine theory. At this time, China has accumulated a lot of knowledge in the pharmacological research of single Chinese medicine. From 65438 to 0982, the textbook Pharmacology of Traditional Chinese Medicine was compiled by the state organization, which officially listed Pharmacology of Traditional Chinese Medicine as an important professional course, which promoted the development of the subject. 1985, 10 In June, the Pharmacology Professional Committee of Chinese Pharmacology Society was formally established, and the research direction of traditional Chinese medicine was established. 1June, 985, Wang edited Pharmacology of Traditional Chinese Medicine, which marked the formal formation of China Pharmacology.

Since 1985, the research on the pharmacology of traditional Chinese medicine compound has been in full swing in China, and great achievements have been made, which has attracted great attention from the state. 165438 June 1996 to165438 October 1996, the study of compound prescription of traditional Chinese medicine was listed as one of the difficulties and breakthroughs in the theoretical research of traditional Chinese medicine in the 2/kloc-0 century. During the Ninth Five-Year Plan period, China formulated a strategic plan for the modernization of traditional Chinese medicine, one of which focused on the modern research of traditional Chinese medicine compound, in which the main goal was to clarify the material basis and action principle of traditional Chinese medicine compound. A number of major or key projects have been set up to support the research on scientific issues related to the modernization of traditional Chinese medicine. For example, 1998 initiated the pre-selection project of basic research on key issues of modernization of traditional Chinese medicine in the Ninth Five-Year Plan; From 65438 to 0999, the Ministry of Science and Technology launched the national key basic research development planning project (973 project) "Basic research on key problems of prescriptions-principles and method and innovation", which was unprecedented in the field of Chinese medicine research, greatly promoted the pharmacological research of Chinese medicine compounds and entered a brand-new historical stage.

The study of pharmacology of traditional Chinese medicine began with a single traditional Chinese medicine, among which the most famous discoveries are ephedrine, artemisinin, camptothecin and hydroxycamptothecin. With regard to the research of traditional Chinese medicine compound prescription, China has mainly carried out three aspects of research: traditional ancient prescription research, modern empirical prescription research and compound compatibility relationship research, among which Siwu decoction and Liuwei Dihuang decoction are more studied. Therefore, the pharmacological research of modern compound Chinese medicine has developed from simple pharmacodynamic research to comprehensive research on action mechanism, composition and compatibility law.