Traditional Culture Encyclopedia - Almanac inquiry - What medicine is trimethoprim cream? What's the role? Come on, everybody, 3Q.
What medicine is trimethoprim cream? What's the role? Come on, everybody, 3Q.
Drug Name of Trimethoxine Cream Generic Name: Trimethoxine Cream Trade Name: Trimethoxine Cream English Name: Chinese Pinyin: qumixinrugao Ingredients This product is a compound preparation. Its components are 100mg miconazole nitrate and 30000 units neomycin sulfate per100 g. This product is milky white ointment with emulsion as the matrix. Indications of action category are used for rash; Contact dermatitis, seborrheic dermatitis, neurodermatitis, tinea corporis, tinea cruris, tinea manus and pedis, etc. Gauge 10g Usage and dosage for external use. Directly apply to the affected part of the skin, 2-3 times a day. Adverse reaction: 1. Allergic reactions may occur when local drugs are used. 2. There may be burning sensation, itching, tingling and congestion of the skin. 3. Long-term use can cause local skin atrophy, telangiectasia, hirsutism and secondary infection. Precautions are prohibited for patients who are allergic to the ingredients of this product. In order to avoid recurrence, the course of treatment of cutaneous candidiasis and various tinea diseases should be at least 2 weeks, and tinea pedis should be at least 1 month. 2. When treating candidiasis, avoid local close coverage of dressing. 3. Avoid long-term heavy use. Drug treatment for pregnant and lactating women is not clear. Children should be cautious when taking drugs for a long time. Drug interactions in the elderly If you are using other drugs for external use, please consult a doctor or pharmacist before using this product. Toxicology of drug overdose 1. Pharmacology Viconazole nitrate is a broad-spectrum antifungal drug, which can inhibit the growth of most fungi at the concentration of P450 mg/L. This product inhibits the biosynthesis of ergosterol, the main sterol in fungal cell membrane, damages the fine pleura of fungi, changes its permeability, and leads to the leakage of important substances in cells. This product can also inhibit the biosynthesis of triacylglycerol and phospholipids of fungi, inhibit the activities of oxidase and peroxidase, cause the accumulation of hydrogen peroxide in cells, and lead to the degeneration of cell ultrastructure and cell necrosis. Candida albicans can inhibit the transformation of spores into invasive mycelium. Triamcinolone acetonide acetate and topical glucocorticoid have anti-inflammatory, antiallergic and vasoconstrictive effects. Salicylic acid has anti-inflammatory and exfoliating effects. Neomycin sulfate has a good effect on Staphylococcus (methicillin-sensitive strains) and Corynebacterium, and also has a good effect on Enterobacteriaceae such as Escherichia coli, Klebsiella, Proteus and so on. The activity of streptococcus, streptococcus pneumoniae and enterococcus is poor, and Pseudomonas aeruginosa and anaerobic bacteria are resistant to this product. Bacteria have partial or complete cross-resistance to streptomycin, neomycin, kanamycin and gentamicin. 2. Toxicology has no irritation to the skin and mucosa of rabbits and mice. Pharmacokinetics is only slightly absorbed after local application.
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