Have you checked for thalassemia before marriage?

Nowadays, people don't get married as before. Parents arrange marriage and choose a lucky wife to marry. Before getting married, you have passed the necessary procedures, and the marriage examination is one of them. Before marriage, both husband and wife are a simple test, which is for the happiness after marriage. So, have you checked for thalassemia before marriage? If you want to know about this, let's take a look!

Have you checked for thalassemia before marriage? Anemia means that hemoglobin (which has the function of carrying oxygen and is the main component of red blood cells) is lower than normal, and hemoglobin is composed of heme and globin. Globin contains four kinds of peptide chains: α, β, γ and δ. HbA(α2β2, the main hemoglobin of adults, accounting for more than 95%), HbA2(α2δ2, accounting for 2-3%) and HbF(α2γ2, accounting for only 65,438+0% after 6 months of birth) are composed of α chains and non-α chains (β, γ, δ) in turn. Alpha and beta thalassemia are the two most common thalassemia, which can reduce the expression of alpha and beta chains respectively, thus affecting the synthesis of hemoglobin.

The screening of thalassemia is hemoglobin electrophoresis, and the report will have the values of HbA, HbA2 and HbF. If HbH or Hb bart can be detected, there will be corresponding data.

The results of thalassemia screening for mild α thalassemia can be normal. If there are small cells with low pigmentation in blood routine, genetic testing is needed. HbH can be found in thalassemia screening of HbH disease. Hb bart can be seen in the comprehensive screening of fetal edema and poverty, but most of them died in the palace and had no chance to be tested.

The father is a standard thalassemia, α-/α-,which means that each chromosome 16 is missing an α gene, and the mother is α-,which means that one chromosome 16 is normal and one chromosome 16 is missing two α genes. Only the offspring passed down by the father have α-,and the probability of being passed down by the mother is α-,and the probability is half. In other cases, we can use biological knowledge to infer probability.

Premarital pregnancy test. What? 1, liver function.

Liver function test is mainly to check the big liver function, blood sugar and bile acid of girls; This test is usually carried out in the first three months of pregnancy, and the main purpose is to check whether girls have hepatitis. If they have hepatitis, it will lead to premature delivery and may also lead to the risk of hepatitis being transmitted to their children. This test is usually an intravenous blood test.

2. Chromosome abnormality

Chromosome abnormality is mainly to check whether you have genetic diseases; This examination is usually carried out in the first three months of pregnancy; Generally, venous blood drawing is enough.

3. oral examination

Oral examination is mainly aimed at female students' dental examination. If you have the symptoms of toothache, it will have a great impact during pregnancy, so you can't take medicine at the same time, so it is best to check it half a year before pregnancy, and you can deal with it in time if there is any problem.

Pre-marital examination is the most important physical examination before modern marriage, which is mainly for the sake of the other person's health, removing unfavorable obstacles for marriage, and also bringing protection to the other person's marriage life.