Pathogens causing acute necrotizing enterocolitis are

Acute necrotizing enterocolitis is related to enterotoxin produced by Clostridium perfringens type C, and P toxin produced by Clostridium perfringens can be hydrolyzed by intestinal trypsin and lose its pathogenic effect. Children with long-term malnutrition and children who often eat foods rich in trypsin inhibitors will significantly reduce the activity of intestinal trypsin and increase the chance of illness.