What kind of medication do you take for endo-rheumatoid arthritis? Eat what?

Rheumatoid arthritis is a chronic, systemic autoimmune disease. The main manifestations are symmetrical hands, wrists, feet and other multiple joint pain, swelling and stiffness.

The drugs used to treat rheumatoid arthritis mainly include:

1, non-steroidal anti-inflammatory drugs (NSAIDs): they have analgesic, anti-inflammatory and antipyretic effects, and are commonly used to alleviate the symptoms of arthritis. Commonly used drugs include ibuprofen, diclofenac and so on. Major adverse effects include gastrointestinal, hepatic and renal impairment, as well as a possible increase in cardiovascular adverse events. Drug selection should avoid concomitant administration of two or more NSAIDs, and regular monitoring of blood counts and liver and renal function is required.

2, traditional anti-rheumatic drugs: these drugs are slower than NSAIDs, do not have obvious analgesic and anti-inflammatory effects, but can delay and control the progress of the disease. Methotrexate is the drug of choice for the treatment of rheumatoid arthritis, and is also the basic drug for combination therapy, with adverse reactions such as hepatic damage, gastrointestinal reactions, bone marrow suppression and stomatitis. The main adverse effects of leflunomide include gastrointestinal reactions, liver damage, alopecia, bone marrow suppression and hypertension, and it is contraindicated in pregnant women because of its teratogenic effects. Antimalarials include hydroxychloroquine and chloroquine, with the former being more commonly used, and funduscopy is required before and during treatment to monitor for possible retinal damage caused by the drug. Sulfasalazine is started in small doses, which will reduce adverse effects, and should be used with caution in those who are allergic to sulfa. Prominent adverse effects of cyclosporine are increased blood creatinine and blood pressure, and close monitoring is advisable while taking the drug.

3, biological anti-rheumatic drugs: is currently active and effective control of inflammation is an important drug, can reduce bone destruction, reduce hormone dosage and osteoporosis. Currently the most commonly used are tumor necrosis factor (TNF)-α antagonist, interleukin (IL)-6 antagonist. To increase efficacy and minimize adverse effects, this class of biologics is recommended to be used in combination with methotrexate. Major side effects include injection site reactions and infusion reactions, which may increase the risk of infection, especially tuberculosis infection, and some biologics increase the potential risk of developing tumors with prolonged use. Screening for tuberculosis, except for active infections and tumors, should be done before using the drug.

4, glucocorticoids: powerful anti-inflammatory effect, can quickly relieve the symptoms of joint swelling and pain and systemic inflammation. The principle of treatment is small dose, short course.

5, phytopharmaceutical preparations: have a better effect on relieving joint symptoms. Such as tretinoin, paeonia lactiflora total glucoside, cymbopogonin, etc.. Among them, tretinoin is most commonly used, and attention should be paid to its gonadal suppression, bone marrow suppression, liver damage and other side effects.

The symptoms of rheumatoid arthritis should be timely to the regular hospital, do not abuse prescription, secret prescription, do not self-medication, so as not to delay the condition. If the effect of the above drug treatment is not good, and the patient appears joint deformity, seriously affecting the joint function, can consider surgery.