How is cirrhosis treated?

Cirrhosis is a common clinical chronic progressive liver disease, formed by one or more causes of long-term or repeated effects of diffuse liver damage. In our country most of them are post hepatitis cirrhosis, and a few are alcoholic cirrhosis and schistosomal cirrhosis. Pathohistologically, there are extensive hepatocellular necrosis, nodular regeneration of residual hepatocytes, proliferation of connective tissue and formation of fibrous septa, leading to destruction of the structure of hepatic lobules and formation of pseudo lobules, and the liver gradually deforms, hardens and develops into cirrhosis. In the early stage, there are no obvious symptoms due to the strong compensatory function of the liver, but in the later stage, liver function damage and portal hypertension are the main manifestations, and there are multi-systemic involvement, and upper gastrointestinal hemorrhage, hepatic encephalopathy, secondary infections, hypersplenism, ascites, and carcinoma and other complications are often seen in the late stage.

Treatment:

Cirrhosis is a liver dysfunction due to tissue structure disorder. There is currently no cure. It mainly lies in early detection and stopping the progression of the disease.

Treatment for cirrhosis

1. Supportive treatment

Intravenous hypertonic glucose solution to supplement calories, the infusion can be added to vitamin C, insulin, potassium chloride and so on. Pay attention to maintain water, electrolyte, acid-base balance. In the more serious cases, albumin and fresh plasma can be imported.

2. Hepatitis active stage

Can be given to protect the liver, lower the enzyme, yellowing and other treatments: such as hepatic tylenol, vitamin C. If necessary, intravenous infusion therapy, such as hepatocyte growth promoter, reduced glutathione, glycyrrhetinic acid preparations.

3. Oral drugs to reduce portal pressure

(1) Cardiac glycosides should be given in increments, starting with a small amount.

(2) Nitrates such as analgesics.

(3) Calcium channel blockers, such as cardiac glycosides, can be given sublingually in an emergency.

(4) Supplementation of B vitamins and digestive enzymes, such as Vicodin and Dagi.

(5) the treatment of hypersplenism can be taken to raise white blood cells and platelets of drugs, if necessary, feasible splenectomy or splenic artery embolization treatment.

(6) the treatment of abdominal fluid ① general treatment, including bed rest, restriction of water, sodium intake. ② Diuretic treatment . ③Repeatedly put a large amount of peritoneal fluid plus intravenous infusion of albumin . Increase the plasma colloid osmotic pressure. Regularly infuse plasma or albumin intravenously in small amounts several times a week. ⑤ Concentrated infusion of peritoneal fluid is used for the treatment of refractory peritoneal fluid, or patients with hypovolemia, hyponatremia, hypoproteinemia, and hepatorenal syndrome, as well as patients with large amounts of peritoneal fluid due to various reasons who need to relieve their symptoms urgently. (6) Peritoneo-jugular venous drainage i.e. PVS. (7) Transjugular intrahepatic portosystemic shunt.

(7) Surgical treatment of portal hypertension?

(8) Liver transplantation?