Why you can't do nucleic acid less than 48 hours after vaccination

If a nucleic acid test is needed after vaccination, it should be done 24 hours after leaving the vaccination unit.

New crown vaccine in the production process, the use of new crown virus wild strain after culture, inactivation and other processes to prepare, so that the virus inactivation lost activity, no pathogenicity; lost the ability to replicate the virus in the cell; K and retained his antigenicity, but also relatively retained the integrity of the viral nucleic acid fragments.

We are inoculated with the new crown vaccine, health care workers in the opening of the bottle cap, extraction of vaccine solution, evacuation of gas, extraction after the vaccine bottle, syringe will have residual liquid, in the form of liquid or aerosol contaminated with the operating table of the vaccination, the operator's hands, etc., in the implementation of the process of inoculation, may be contaminated with our skin, clothing and other items. Therefore, if nucleic acid testing is needed after vaccination with the new coronavirus vaccine, sampling should be done after the nucleic acid fragments have been degraded 24 hours after vaccination, which can reduce the number of positive results of nucleic acid testing for the new coronavirus caused by contamination of nucleic acid fragments of the vaccine strain during the vaccination process.

Nucleic acid detection, mainly based on the nucleic acid sequence of each organism DNA is different, as long as the detection of new coronavirus gene sequences in the body, and the use of fluorescence quantitative PCR method, to detect whether the new coronavirus infection. PCR detection is very high sensitivity, if the nucleic acid fragments of the virus before the degradation of the sample, it is likely that the nucleic acid test results positive, resulting in the false impression of infection by the new coronavirus. virus infection.