Rheumatoid specific drug?

1, non-steroidal anti-inflammatory drugs: They have analgesic and anti-inflammatory effects and are commonly used drugs to relieve arthritis symptoms. Commonly used drugs are ibuprofen, diclofenac and indomethacin. The main adverse reactions include gastrointestinal tract, liver and kidney damage, and may increase cardiovascular adverse events. Taking two or more NSAIDs at the same time should be avoided. Topical non-steroidal anti-inflammatory drugs, such as ketoprofen gel and piroxicam patch, have certain effects on relieving joint swelling and pain with few adverse reactions.

2, traditional anti-rheumatic drugs: can delay and control the progress of the disease. Commonly used drugs include methotrexate, leflunomide, hydroxychloroquine, azathioprine and cyclosporine. The main adverse reactions of leflunomide are gastrointestinal reaction, liver injury, alopecia, bone marrow suppression and hypertension, which have teratogenic effects and are prohibited for pregnant women. The prominent adverse reaction of cyclosporine is the increase of serum creatinine and blood pressure, so it should be closely monitored during the medication.

3. Biological anti-rheumatic drugs: It is an important drug to actively and effectively control inflammation at present, which can reduce bone destruction, reduce hormone dosage and reduce osteoporosis. At present, the most commonly used are tumor necrosis factor-α antagonists and interleukin -6 antagonists. The commonly used drugs of tumor necrosis factor-α antagonists are etanercept, infliximab and golizumab. The main side effects of these drugs include injection site reaction and infusion reaction, which may increase the risk of infection, especially tuberculosis infection. Long-term use of some biological agents will increase the potential risk of cancer. Tuberculosis should be screened before medication, except for active infection and tumor. The common adverse reactions of interleukin -6 antagonists are infection, gastrointestinal symptoms, rash and headache.