Traditional Culture Encyclopedia - Traditional culture - Benefits or importance of using animals for drug experimentation What is the significance of this
Benefits or importance of using animals for drug experimentation What is the significance of this
The stages of drug experimentation are divided into in vitro experimentation, animal experimentation and clinical experimentation (human), and animal experimentation is a necessary stage before a drug is applied to the human body. Drugs into the human body, resulting in the impact is likely to be irreversible, the negative effects often bring pain or even endanger the life of the human body, so it is necessary to go through a large number of long-term animal observation, we are not willing to be a test subject ah, so the use of the human body and the structure and function of the animal is very similar to the very reasonable. Its significance mainly includes
Drugs after in vitro experiments, its stability and chemical properties of the formation of the understanding of the animal in vivo testing, can effectively observe the drug in the body of the animal absorption, distribution and metabolism, at the same time, can be timely and effective anatomical experiments on the experimental body, to observe the impact of the drug on the different tissues and organs caused by the effect of the route of action (the target point).
The experimental animals have been strictly screened and artificially bred, and the experimental subjects are those that meet the specific requirements, and the sample size is large, which can effectively evaluate the efficiency and safety of the drugs.
Can help determine the safe dose range of drug application, to avoid the damage caused by excessive dose
Inexpensive, good health economics
Easy to centralize the management
Conducive to the avoidance or reduction of the incidence of adverse reactions to drugs in the human body, the significance of the dead people and dead animals is far too much difference, so the choice of sacrificing some of the animals is a must.
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