What do you mean by sequential booster of COVID-19 vaccine (can COVID-19 vaccines from different manufacturers be vaccinated sequentially? )

1. What do you mean by sequential immunization?

Sequential booster immunization is heterologous booster immunization, which refers to COVID-19 vaccine with different technical routes when selecting booster immunization. For example, the inactivated vaccine was inoculated before. If the inactivated vaccine is selected for booster immunization, it is homologous booster immunization, while if the COVID-19 vaccine is selected for non-inactivated process, it is called sequential booster immunization.

At present, there are three kinds of COVID-19 vaccines in China: inactivated vaccine, adenovirus vector vaccine and recombinant protein vaccine.

Inactivated vaccine is to produce live virus first, and then inactivate the virus by physical or chemical methods to make it vaccine immunity;

Adenovirus vector vaccine is to insert the most effective virus antigen gene into adenovirus genome, infect human cells through adenovirus, introduce genes into human cells, and human cells express antigens to stimulate human immune response.

Recombinant protein vaccine is the most effective antigen component expressed in vitro through genetic engineering, and cells are often used in biological products. This cell produces this protein through a way similar to industrial fermentation, that is, a bioreactor, and finally it is made into a vaccine.

Second, who can carry out sequential immunization?

1 and1people over 8 years old.

2. Two doses of inactivated vaccine should be inoculated, which are COVID-19 inactivated vaccine from Sinopharm Zhongsheng Beijing Company, Beijing Kexing Company and Sinopharm Zhongsheng Wuhan Company.

3, complete the whole process of two doses of vaccination, sequential immunization interval should not be less than 6 months.

4, did not strengthen immunity, that is, the third needle did not play.

Generally speaking, at this stage, people who have been vaccinated with inactivated vaccines of Sinopharm Zhongsheng Beijing, Kexing Zhongwei and Sinopharm Zhongsheng Wuhan COVID-19 for six months and have not completed homologous booster immunization can be given sequential booster immunization.