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The discovery of artemisinin by Tu Youyou gives people what insights

Tu Youyou's spirit, there is a more admirable, worthy of learning is in the scientific research work of dedication, obscurity and work attitude. Before she won the prize, no one knew who she was, and she didn't care what kind of house she lived in or whether she was an academician.

Maybe so many research workers, before getting a satisfactory and successful conclusion, are obscure, or long hours are consumed in figuring out the road. But there is no serious spirit of selfless sacrifice as a prerequisite more will not ascend to the lighthouse of true knowledge. Therefore, the scientist Tu Youyou has shown us not only the fruit of scientific research, but also the inspiration of the spirit.

The discovery of artemisinin, the basic idea and starting point of this research is based on the theory of traditional Chinese medicine, and eventually did achieve the expected results. Artemisinin-based combination therapies have become the standard anti-malaria treatment recommended by the World Health Organization.

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History of the discovery of artemisinin

May 21, 1971 ~ June 1, the National Symposium on Malaria Prevention and Control Research was held in Guangzhou, after the meeting, the Institute of Traditional Chinese Medicine in Beijing re-organized the research group, Tu Youyou is still the leader of the team, and members of the group Zhong Yurong continue to extract the traditional Chinese medicine, Lang Linfu and Liu Jufu to do The animal tests were carried out by Lang Linfu and Liu Jufu.

According to the drug screening records of the Beijing Institute of Traditional Chinese Medicine, the inhibition rate of Artemisia annua was 12% on July 26, 1971 (Serial No. 16), 40% on September 1 (Serial No. 114), and 100% on October 4 (Serial No. 191), and the inhibition rate of Artemisia annua was 100% on October 4 (Serial No. 191), and Tu Youyou's group started to extract large quantities of Artemisia annua ethyl ether extract from it in January 1971, and completed toxicity tests on dogs in June. In January 1971, Tu Youyou's group began to extract large quantities of Artemisia annua ether extract, and at the end of June of that year, completed the toxicity test in dogs.

In order to carry out clinical trials as soon as possible, while the results of the toxicity test of Artemisia annua ether extract on dogs were still controversial, Tu Youyou, Lang Linfu, Yue Fengxian, and Zhang Guozhen, Yan Shuchang, Pan Hengjie, Zhao Aihua, and Fang Wenxian successively carried out self-tests on neutral extracts of Artemisia annua ether in two batches with different dosages from June to August, and there were no obvious toxic side effects.

Baidu Encyclopedia-Artemisinin