Traditional Culture Encyclopedia - Traditional festivals - Organic acids that undergo decarboxylation in the tricarboxylic acid cycle are
Organic acids that undergo decarboxylation in the tricarboxylic acid cycle are
Tricarboxylic acid cycle (TCA cycle) is a common metabolic pathway in aerobic organisms. It is distributed in cytoplasm in prokaryotes and mitochondria in eukaryotes. Because several main intermediate metabolites in this cycle are organic acids containing three carboxyl groups, such as citric acid (C6), it is called tricarboxylic acid cycle, also called citric acid cycle or TCA cycle.
Or named after the discoverer hans adolf krebs (1953 Nobel Prize winner in physiology or medicine). Tricarboxylic acid cycle is the ultimate metabolic pathway of three nutrients (sugar, fat and amino acid), and it is also the hub of metabolic connection of sugar, fat and amino acid.
? Analysis:
Citric acid cycle: also known as tricarboxylic acid cycle (TCA cycle, TCA cycle) and Krebs cycle. This is a circulatory system of enzymatic reaction that oxidizes acetyl group in acetyl coenzyme A into carbon dioxide and reduces equivalent. The first step of this cycle is the condensation of acetyl coenzyme A with oxaloacetic acid to form citric acid. Acetyl-CoA (CoA molecule linked to acetyl group) is an intermediate product of carbohydrate, lipid and amino acid metabolism.
After entering the circulation, it will decompose and finally produce carbon dioxide and generate H, which will be converted into coenzyme I- nicotinamide adenine dinucleotide (NAD+). (or nicotinamide adenine dinucleotide) and flavin adenine dinucleotide (FAD), making it NADH+H+ and FADH2. NADH+H+ and FADH2 carry H into the respiratory chain, and the respiratory chain transfers electrons to O2 to generate water, while coupling oxidative phosphorylation to generate ATP to provide energy.
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