Traditional Culture Encyclopedia - Traditional stories - What method is used to reduce tangential flow for agitation of dispensing tanks such as aqueous injections, and why?
What method is used to reduce tangential flow for agitation of dispensing tanks such as aqueous injections, and why?
Tangential flow mixing. Because the preparation of aqueous injections and other pharmaceutical liquids are prone to high concentrations of drugs localized aggregation or precipitation phenomenon, which will affect the uniformity and stability of the liquid.
Traditional radial mixing will cause a wide range of liquid shear stress, so that the local concentration change is more obvious, while the tangential flow mixing can reduce the shear stress, so that the liquid is more smoothly rotating, homogeneous mixing and maintain its stability.
Tangential flow mixing has other advantages, such as the ability to quickly mix the liquid in a short period of time to reduce the generation of foam, and equipment structure is simple and easy to operate and maintenance and other advantages, so tangential flow mixing in the production of pharmaceuticals, manufacturing and other fields are widely used.
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