Traditional Culture Encyclopedia - Traditional stories - What are the benefits of experimenting with animals
What are the benefits of experimenting with animals
Inbred animals are genetically homogeneous, so they can be used to obtain highly accurate experimental results, which is valuable in medical research. Why is it necessary to breed F1 animals that are crosses between two different inbred lines? This is because inbred animals, compared with hybrids, have poorer vitality, resistance to diseases and tolerance to chronic experiments, are less adaptable to environmental changes, and are more difficult to breed and raise. Under general equipment conditions, if chronic experiments are to be carried out, long-term observation is required, and if the animals die halfway, the experiments will not be as effective as expected. On the other hand, F1 animals have more or less overcome the shortcomings of pure lines due to the hybridization advantage, and are more tolerant to long-term experiments, and are less likely to mutate due to environmental factors than pure lines. Therefore, F1 animals are the same as inbred animals, they have genetic homogeneity, but they are strong, after hybridization, the recessive harmful genes from one parent and the dominant favorable genes from the other parent are combined to become heterozygous, and the role of recessive harmful genes is masked by the role of dominant favorable genes, and the emergence of hybrid dominance. In summary, F1 animals have the following advantages: 1. They have the advantages of crossbreeding, strong vitality, adaptability and disease resistance, and vigorous reproduction, which to a large extent can overcome the phenomenon of inbreeding decline caused by inbreeding. 2. They are basically similar to purebred animals. 2. It has the genetic homogeneity which is basically similar to that of pure animals. Although its genes are not pure, but the genotype is neat and consistent, the heredity is stable, and the phenotype is also consistent, so it basically has the characteristics of inbred animals. 3. Repeatability of the results of various experiments is good. 4. It has the characteristics of parental biparental. 5. Widely distributed internationally and widely used in all kinds of experimental research, the experimental results can be easily repeated and exchanged internationally. The above characteristics of F1 animals, explaining why there are inbred animals, but also to cultivate F1 animals. Some developed countries in the past on the microorganisms have not generally achieved artificial control period, is superior to the development of F1 animals. In view of China's current material conditions, should be well developed F1 production, publicize its scientific value.
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