Preparation technology of traditional Chinese medicine of sijiqing

1. sijiqing tablets: sijiqing 4000g. Dry and pulverizing a prop amount of Chinese holly leaf into fine powder, decocting that rest in wat twice, concentrating the filtrate to about 2000ml, adding 4000ml of ethanol, stirring, standing, concentrating the supernatant into paste, adding 4 times of water, stirring, standing for precipitation, concentrating the supernatant into thick paste, adding Chinese holly leaf fine powder, mixing, drying, pulverizing, granulating, and pressing into 1000 tablets. Each tablet is equivalent to 4g sijiqing. After removing the sugar coating, it is brown; It tastes bitter and astringent. For the quality identification of this product, see "Physical and Chemical Identification" of medicinal materials. Functional convergence, antibacterial. Used for acute and chronic pharyngolaryngitis, dysentery and urinary tract infection. Oral administration, 5 tablets each time, 3 times a day. [People's Republic of China (PRC) Pharmacopoeia1977; Ministry of Health Drug Standards and Prescriptions of Traditional Chinese Medicine (Volume II) 1990]

2. Compound Sijiqing tablets: 400g of dry extract of Sijiqing and 30g of houttuynia cordata Thunb. Decocting Cortex Ilicis Rotundae in water twice, collecting filtrate, clarifying, concentrating, and drying at 65438 000℃ to obtain dry extract; Mixing the dry extract of Chinese holly leaf with synthetic houttuynia cordata Thunb. By increasing the amount, adding appropriate amount of auxiliary materials, pressing into 1000 tablets, and sugar coating. The core without sugar coat is brown; It tastes fishy and astringent. Grinding the product, adding ethanol, slightly heating, filtering, and dripping ferric chloride test solution into the filtrate, and the filtrate is blue-purple; Grinding the product, adding 0.05mol/L sodium hydroxide solution, dissolving, filtering, taking 65438 0 ml filtrate, adding 65438 0 ml 2,4-dinitrophenylhydrazine test solution, and heating to generate reddish-brown precipitate; Take 2 tablets of this product, dissolve them in alkaline water, and then shake and extract them with weak acid ethyl acetate solution. Take the ethyl acetate layer as the test solution, take 20mg of artificially synthesized Houttuynia cordata Thunb, and take the ethyl acetate layer as the control solution in the same way. 2 mg of protocatechuic acid was dissolved in absolute ethanol to make a solution. On the silica gel G-CMC thin-layer plate, 65,438+test solution, reference solution and protocatechuic aldehyde solution were respectively spotted. Using benzene-anhydrous ethanol (7: 2), taking it out, drying it, and using 5% ferric chloride test solution to develop color, the test sample obviously presents yellow spots corresponding to the synthetic Houttuynia cordata Thunb reference substance and dark blue spots corresponding to protocatechuic acid. Function: clearing away heat and toxic materials, resisting bacteria and diminishing inflammation. Used for upper respiratory tract infection, pharyngolaryngitis, tonsillitis and acute and chronic bronchitis. Oral administration, 2-4 tablets each time, 3 times a day. (Shanghai Drug Standard 1980)

3. Compound Holly Oil Yarn: Holly150g, Rhubarb120g, Arnebia euchroma 90g, honeysuckle 60g, borneol 9g and vaseline1500g. Except Borneolum Syntheticum, the other four herbs were ground into powder. After the vaseline melts, add Arnebia euchroma, fry lh with slow fire, and when the oil turns purple, add Holly, rhubarb and honeysuckle. Stir constantly, continue to fry for 30 minutes, filter off the residue, add borneol and stir evenly, pour the liquid medicine into a box filled with gauze strips to make oil gauze, and sterilize for later use. It can be used for treating erosive, ulcerative and persistent drug eruption. Apply externally to the affected area, cover it with sterile gauze and fix it with adhesive tape, and change the dressing every 1-2 days/time. [Chinese Journal of Dermatology 198 1, 14 (4): 225]

Source of medicinal materials

It is the leaf of Ilex pubescens.

dosage

Oral administration: decoction, 15-30g. External use: appropriate amount, freshly pounded; Or decocting, washing, and coating with water.

source

A cursive script