Structural modification principle of artemisinin

Artemisinin is a sesquiterpene compound isolated from Artemisia annua.

Artemisinin is an organic compound with the molecular formula of C 15H22O5 and the relative molecular weight of 282.34. Artemisinin is a colorless needle-like crystal with melting point of 156 ~ 157℃. Soluble in chloroform, acetone, ethyl acetate and benzene, soluble in ethanol and ether, slightly soluble in cold petroleum ether and almost insoluble in water. Because of its special peroxy group, it is unstable to heat and easy to be decomposed by wet, hot and reducing substances.