What is a recombinant COVID-19 vaccine? (What is a recombinant COVID-19 vaccine)

What is a recombinant COVID-19 vaccine?

The recombinant COVID-19 vaccine used in Yichang was jointly developed by Institute of Microbiology of China Academy of Sciences and Anhui Zhifeilong Kyle Company. Its principle is to recombine the new coronavirus S protein receptor binding region gene into China hamster ovary gene, express it in vitro to form RBD dimer, and add aluminum hydroxide adjuvant to improve immunogenicity. Its technical principle is similar to that of mature hepatitis B CHO cell vaccine.

What is the safety and effectiveness of recombinant COVID-19 vaccine?

Like COVID-19 inactivated vaccine and adenovirus vector vaccine, recombinant COVID-19 vaccine has been approved by National Medical Products Administration, which has good safety and immune effect and can play a good protective role.

According to the clinical trial results of Xinguan pneumonia vaccine and the information collected during emergency use, the common adverse reactions of recombinant COVID-19 vaccine are basically similar to other vaccines that have been widely used. The main manifestations are redness, induration and pain at the inoculation site, and the clinical manifestations are fever, fatigue, nausea, headache and muscle pain. Generally speaking, these symptoms are mild and do not need special treatment.