What are the treatment prescriptions for rheumatoid arthritis?

Rheumatoid arthritis is a multi-system inflammatory autoimmune disease, which mainly involves peripheral joints. Its characteristic symptoms are the symmetry of multiple joints and chronic inflammatory lesions around it. The clinical manifestations are pain, swelling and hypofunction of the affected joint, and the lesion is in the process of persistent and repeated attacks.

This disease belongs to the category of "arthralgia syndrome" in traditional Chinese medicine, and its occurrence is mainly due to deficiency of liver and kidney, weakness of qi and blood, invasion of human body by wind-cold, dampness and heat, and obstruction of qi and blood caused by flowing into meridians. The treatment method is mainly to eliminate evil and activate collaterals, and to relieve pain urgently. Eliminate pathogenic factors, tonify spleen and liver and kidney to strengthen the body resistance by expelling wind and cold, eliminating dampness and clearing heat, promoting blood circulation and dredging collaterals.

Fang Yi Modified Tongfeng Prescription (Wang Lvqiu)

Source "Records of Famous Doctors"

It consists of raw ephedra10g, cassia twig10g, prepared atractylodes macrocephala10g, cooked aconite root10g, radix Saposhnikoviae10g, radix stephaniae tetrandrae10g and radix clematidis/kloc-0.

Function of expelling wind and removing dampness, resolving phlegm and removing blood stasis.

Indications: rheumatoid arthritis. Symptoms include swelling and pain of fingers and toes, even hard deformation, unfavorable mouth opening, or swelling and pain of limbs, light and slightly greasy tongue coating, and thin and astringent pulse.

Ephedra in the prescription diverges wind and cold; Atractylodes lancea tastes bitter, warm and dry; Fuzi warms meridians to dispel cold; Rheumatism; Guizhi dispels the wind in the sky; Protect yourself from moisture; Clematis leads to the twelve meridians, expelling wind and dredging collaterals; Nanxing phlegm dampness; Peach kernel promotes blood circulation and removes blood stasis; Spatholobus suberectus promotes blood circulation and nourishes blood; Scorpion hives search for wind and remove collaterals; Tripterygium wilfordii will dispel wind and detoxify.

Pharmacology Ephedra has antipyretic and anti-inflammatory effects, which can obviously reduce the capillary permeability of abdominal cavity and inhibit the inflammatory reaction caused by carrageenan. Ephedra has analgesic effect; In addition, ephedra can also inhibit hemolytic streptococcus in vitro. Guizhi has obvious anti-inflammatory and anti-allergic effects. Atractylodes lancea can eliminate immune complexes in animals. Radix Aconiti Lateralis has adrenocortical hormone-like effects.

Usage: decoct in water, daily 1 dose, twice per dose, and the first decoction time should not be less than 45 minutes.

Fang er re bi yin

Source: Records of Famous Doctors' Prescriptions, Fourth Series

Comprises Radix Angelicae Sinensis 12g, Radix Scutellariae 9g, Fructus Forsythiae 12g, Flos Lonicerae 12g, Semen Coicis 24g, Radix Saposhnikoviae 12g, Radix Stephaniae Tetrandrae 12g, Cortex Erythrinae 15g, and Radix Glycyrrhizae.

Function of clearing heat and promoting diuresis, dredging arthralgia and collaterals.

Indications: rheumatoid arthritis. It belongs to heat arthralgia syndrome with damp-heat as the main factor, wind-cold as the combination, cold and heat mixed with excess and deficiency, and qi and blood running poorly.

Angelica sinensis in the prescription nourishes blood and promotes blood circulation, and is good at stopping muscles, joints and neuralgia; Scutellaria baicalensis Georgi clearing heat and drying dampness; Glycyrrhiza uralensis Fisch regulates various drugs to relieve pain; Saposhnikovia divaricata, arthralgia due to wind-cold-dampness, antipyretic, analgesic and analgesic effects; Prevent yourself from getting cold and giving off heat; Pittosporum bark can dispel wind and remove dampness, dredge meridians, reduce swelling and relieve pain; Forsythia rose and floated, promoting qi and blood, and expelling the heat of meridians; Coix seed dehumidification does not help dryness, clearing heat does not hurt yin, benefiting qi does not nourish damp heat; Honeysuckle has the functions of clearing away heat and toxic materials, dredging meridians and regulating qi and blood. Combination of nine drugs, clearing away dampness and heat, dispersing stagnation and removing arthralgia.

Pharmacology Angelica sinensis has obvious inhibitory effect on acute exudative inflammation, also has certain effect on allergic inflammation, and can relieve pain. Scutellaria baicalensis Georgi has anti-inflammatory effect, which can prevent and protect the secondary damage of adjuvant arthritis in rats and inhibit bone degeneration and destruction. And has an in vitro inhibitory effect on streptococcus. Forsythia suspensa has obvious anti-inflammatory effect, which can significantly inhibit inflammatory exudation and edema. Radix Saposhnikoviae and Radix Stephaniae Tetrandrae also have anti-inflammatory effects.

Usage: Take it in water, 1 dose twice, the first time in the morning and the second time in the afternoon, decoct it in water for half an hour, and take it 1 hour after meals, daily 1 dose.

Fangsanfuzi xixin decoction

Source "journal of traditional chinese medicine, Hubei"

Radix Astragali 60g, Atractylodis Rhizoma 30g, Fructus Lycii 30g, Herba Siegesbeckiae 30g, Radix Aconiti Preparata 12g, Radix Aconiti Kusnezoffii Preparata 12g, Flos Carthami 12g, Gypsum Fibrosum 50g, Rhizoma Anemarrhenae 20g, Olibanum Preparata 15g and Myrrha Preparata/kloc.

It has the effects of clearing away heat and expelling wind, dispelling cold and relieving pain, and simultaneously attacking and tonifying.

Indications: Rheumatoid arthritis with mixed cold and heat.

In the prescription, Radix Aconiti and Radix Aconiti Kusnezoffii dispel cold and relieve pain; Gentiana macrophylla and Herba Siegesbeckiae dispel wind and remove dampness; Astragalus membranaceus, Atractylodes macrocephala and Lycium barbarum are beneficial to qi and blood and support healthy qi; Gypsum and Anemarrhena asphodeloides can clear away heat, detoxify and nourish yin, which can restrict the deviation of two evils. Frankincense, myrrh and safflower promote blood circulation and dredge collaterals.

Pharmacology Astragalus membranaceus, Atractylodes macrocephala and Lycium barbarum have the function of regulating immune function. Radix Aconiti Preparata has anti-inflammatory and analgesic effects on experimental arthritis. Herba Siegesbeckiae has the functions of anti-inflammation, inhibiting cellular immunity and humoral immunity, dilating blood vessels and improving microcirculation. Frankincense, myrrh and safflower can improve blood circulation, increase tissue oxygen supply and promote inflammatory absorption.

Usage: 1 dose daily, decocted twice, each dose decocted 1 hour, and decocted 300 ml of liquid medicine, three times a day, each time 100 ml, taken after meals.

Fangji Bitong Decoction

Source: Guangming Traditional Chinese Medicine

It consists of Zaocys 15g, Bombyx Batryticatus 10g, Eupolyphaga Seu Steleophaga 10g, Hive 10g, Pheretima 10g, Angelica sinensis 10g, Radix Clematidis 30g, Caulis Spatholobi 30g and Radix Glycyrrhizae 6g.

Functions: expelling wind and cold, removing dampness and dredging collaterals, resolving phlegm and removing blood stasis.

Indications: rheumatoid arthritis.

In the prescription, Zaocys dhumnades and Radix Clematidis dispel wind and remove dampness, dredge collaterals and relieve pain. Eupolyphaga Seu Steleophaga, Caulis Spatholobi, Danggui Sanyu Tongluo, Jin Shu Huoxue; Baking stiff silkworm to remove phlegm and loose knot, dredging meridian passage; Guangdilong has the functions of clearing away heat and toxic materials, purging heat and dredging collaterals; Hive rising yang causes arthralgia, detumescence and pain relief; Licorice harmonizes the characteristics of various drugs. The combination of all the medicines has the functions of tonifying kidney, consolidating governor, expelling wind and cold, removing dampness and dredging collaterals, and resolving phlegm and removing blood stasis.

Pharmacological Bombyx Batryticatus has a strong anticoagulant effect in vivo and in vitro. Lumbricus directly inhibits thrombin-fibrinogen reaction and has good anticoagulant and antithrombotic effects.

Usage: daily 1 dose, decocted in water twice.

Jiawei Wu Fang Duhuo Jisheng Decoction

Source: Journal of Traditional Chinese Medicine Emergency

Comprises 35g of Radix Angelicae Pubescentis, 20g of Herba Taxilli, 20g of Eucommiae Cortex 15g, 20g of Achyranthis Radix, 5g of Asari, 20g of Radix Gentianae Macrophyllae, 20g of Poria, 5g of Cinnamomum cassia, 5g of Scorpio, 3g of centipedes, 20g of Saposhnikovia divaricata, 20g of Ligusticum Chuanxiong 15g, 20g of Ginseng Rubra and 20g of Glycyrrhiza uralensis 10.

Functions: expelling wind and removing dampness, removing arthralgia, benefiting liver and kidney, and nourishing qi and blood.

Indications: Rheumatoid arthritis with persistent symptoms, deficiency of liver and kidney and deficiency of both qi and blood.

Fang Zhong's unique skill is king, and he is good at removing common cold, cold and dampness between the lower jiao and the bones and muscles based on the principle of controlling wind. Wu used asarum to disperse yin and channel wind and cold, and searched bones and muscles for rheumatism and pain relief; Rheumatism; Gentiana macrophylla dispels wind and dampness, relaxes muscles and tendons; Taxilli, Eucommia ulmoides and Achyranthes bidentata can dispel wind and remove dampness and nourish liver and kidney; Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Rehmanniae and Radix Paeoniae Alba nourish blood and promote blood circulation; Ginseng Radix Rubri and Poria cocos are beneficial to qi and spleen; Cinnamon warms blood vessels; Scorpion and centipede dredge collaterals and relieve pain.

Pharmacological and pharmacological studies show that Duhuo Jisheng decoction has anti-inflammatory effect and can inhibit paw swelling caused by carrageenan and formaldehyde. It can also relieve pain; Adjust the immune function of the body and improve the phagocytic function of mononuclear macrophages.

Usage: daily 1 dose, decoct with slow fire to obtain 250 ml juice, and take it in the morning and evening.

Liu Fang Duxianzi Decoction

Source: Guangming Traditional Chinese Medicine

It comprises Radix Angelicae Pubescentis 10g, Radix Clematidis 12g, Semen Strychni 1g, Caulis Bambusae 10g, Herba Pini 15g, Radix Saposhnikoviae 10g, Radix Dipsaci 15g and bone.

Functions: expelling wind and removing dampness, nourishing blood and activating blood, dredging collaterals and relieving pain.

Indications: rheumatoid arthritis.

Radix Angelicae Pubescentis, Radix Clematidis, Rhizoma Pinelliae, Radix Saposhnikoviae, and expelling wind and dampness in the prescription; Dipsacus and Rhizoma Drynariae tonify kidney and replenish essence; Ramulus Cinnamomi and Radix Paeoniae Alba harmonize camp and health, dispel wind and promote blood circulation; Angelica sinensis nourishes blood and promotes blood circulation; Semen Strychni can search for wind and activate collaterals, dissipate stagnation and relieve pain; Lumbricus, Scorpio, Pangolin, Zaocys, promoting blood circulation, removing blood stasis, dredging collaterals, relieving pain, expelling wind and removing dampness; Bamboo shavings dispel dampness and regulate stomach.

Pharmacological Radix Angelicae Pubescentis has anti-inflammatory effect, and its components can inhibit the swelling of rats' feet caused by carrageenan and have analgesic effect. The analgesic effect of Semen Strychni is related to the pharmacological effects of exciting the central nervous system, relieving pain and improving microcirculation. Rhizoma Drynariae can promote the absorption of calcium by bones, improve the function of chondrocytes and delay the degeneration of cells.

Usage: decoct in water, 1 dose, twice a day, and decoct each time 1 hour. Take it in the morning and evening for three months.

If you feel sick and dizzy after taking the medicine, you can remove or reduce the nux vomica.

Fangqi Guizhi Shaoyao Mu Zhi Decoction

Source: Shenzhen Journal of Integrated Traditional Chinese and Western Medicine

It consists of cassia twig 15g, radix paeoniae alba 9g, radix glycyrrhizae preparata 6g, Herba ephedrae 12g, Rhizoma atractylodis macrocephalae 12g, Rhizoma anemarrhenae 12g, radix Saposhnikoviae 10g, radix aconiti lateralis preparata 10g and Rhizoma Zingiberis recens/kloc-0.

Functions: expelling wind and removing dampness, warming channels and dispelling cold, nourishing yin and clearing heat.

Indications: active rheumatoid arthritis with mixed cold and heat syndrome.

Ramulus Cinnamomi, Radix Paeoniae Alba, Radix Glycyrrhizae and Rhizoma Zingiberis Recens are added to the formula, which harmonizes nutrition and health. Ramulus Cinnamomi, Herba Ephedrae and Radix Saposhnikoviae are combined to dispel wind and cold; Atractylodes macrocephala strengthens spleen and dries dampness; Ramulus Cinnamomi and Radix Aconiti Lateralis Warming Meridians and Dredging Collaterals; Anemarrhena asphodeloides can nourish yin and clear heat, and at the same time warm and dry various drugs.

Pharmacology Ramulus Cinnamomi has obvious anti-inflammatory and anti-allergic effects. The total volatile oil of Cinnamomum cassia twig has obvious inhibitory effect on acute inflammation and adjuvant arthritis in allergic inflammatory model rats. Radix Paeoniae Alba regulates immunity, and total glucosides of Radix Paeoniae Alba and paeoniflorin have analgesic effects. Anemarrhena asphodeloides has antipyretic and anti-inflammatory effects, and has antipyretic effects on fever caused by Escherichia coli in rabbits, and has obvious inhibitory effects on paw swelling and cotton granuloma caused by carrageenan in rats.

Usage: daily 1 dose, morning and evening 1 time.

Fangba Five Blessingg Sanchong Decoction

Source "Shandong journal of traditional chinese medicine"

It consists of 65438+/-00g of prepared Radix Aconiti (fried first), 65438+/-00g of cooked Radix Aconiti Lateralis (fried first), 8g of scorpion, 2 centipedes, 65438+/-00g of pangolin scales, 65438+/-00g of angelica sinensis, 65438+/-00g of prepared Radix Rehmanniae, 8g of Amomum villosum (added later) and roasted licorice.

Functions: Warming channels and dredging collaterals, resolving phlegm and removing blood stasis, nourishing blood and softening tendons, strengthening spleen and tonifying kidney.

Indications: rheumatoid arthritis.

Fuzi dispels cold and Fuzi dispels wind, and the two drugs are used together to warm channels and dispel cold, remove arthralgia and dredge collaterals; Scorpion, centipede and onychomycosis break phlegm and remove blood stasis, and search for evil; Radix Rehmanniae Preparata and Radix Angelicae Sinensis tonify the kidney, nourish blood and soften tendons, and take sweet and warm Amomum villosum into the spleen, stomach and kidney to treat the lower jiao and warm the spleen and stomach, and even introduce medicine into the kidney. The combination of the three medicines can tonify the liver, spleen and kidney; Glycyrrhiza uralensis Fisch is used to reconcile the properties of drugs and reduce the bias and toxicity of drugs.

Radix Aconiti Preparata has anti-inflammatory and analgesic effects on experimental arthritis. Radix Aconiti Lateralis has adrenocortical hormone-like effect, and the alkaloids contained in it have inhibitory effect on exudative inflammation and analgesic effect. Scorpion has anticoagulant, fibrinolytic and antithrombotic effects. Moreover, scorpion venom contains analgesic peptides, which have a strong analgesic effect on various pain models.

Usage: decoct 400 ml in water and take it twice, daily 1 dose.

Modified Fangjiu Huangqi Guizhi Decoction

Source: Shaanxi Traditional Chinese Medicine

It consists of 20 grams of Radix Astragali and Radix Rehmanniae Preparata, 0/5g of Ramulus Cinnamomi, Radix Paeoniae Alba, Rhizoma Zingiberis Recens, Fructus Jujubae/kloc, 0/5g of Rhizoma Curcumae and Poria/kloc.

Function: benefiting the temperature and yang, nourishing blood and dredging collaterals.

Indications: rheumatoid arthritis, deficiency of both qi and yang. Symptoms include joint swelling and pain, aggravated cold, purple or pale complexion, dull complexion, cold limbs, listlessness, anorexia, frequent urination, loose stool, pale tongue with thin white fur, and weak pulse.

Fang Jie Astragalus strengthens the spleen, benefits the stomach and consolidates the exterior, and promotes diuresis and detumescence; Ramulus Cinnamomi warms the meridians to activate Yang, which makes Yang Can reach the diseased place directly and drive away cold evil. Paeonia lactiflora nourishes blood and benefits the camp, and ginger and jujube reconcile the camp and the guard, so that the blood is full of healthy qi, and the camp and the guard actually resist the invasion of external evils; Turmeric promotes blood circulation and collaterals; Poria cocos can strengthen the spleen and eliminate dampness, prevent nourishing yin and greasy spleen, and eliminate the evil of cold and dampness. The whole prescription focuses on strengthening the body resistance and eliminating evil spirits.

Pharmacological research shows that Guizhi decoction has anti-inflammatory effect, and has obvious inhibitory effect on foot swelling caused by carrageenan and increase of skin capillary permeability caused by xylene. It has a two-way regulation effect on immune function and can reduce the immune function of ADHD; It also has anti-streptococcus and analgesic effects.

Usage: decoct in water, daily 1 dose, each time 100 ml, twice a day.