Wang Chuanxin of Wang Chuanxin

Professor Chuanxin Wang graduated from Shandong University School of Medicine with a doctorate degree in medicine, and has been engaged in clinical, teaching and scientific research in immunology and hematology. He was the first in China to apply platelet microparticle detection in whole blood to the diagnosis of cardiovascular and cerebral vascular diseases, and established a new method of urinary hemoglobin detection, and has been engaged in the research of early diagnosis of tumors and the correlation between tumor-causing viruses and HLA. He has been responsible for the teaching of Clinical Immunology Test, Experimental Diagnostics and the postgraduate course Technology and Progress of Scientific Research Related Techniques in the five-year, six-year and seven-year courses of Shandong University School of Medicine, and was awarded the Outstanding Teacher of Theory Lecture in Qilu Hospital of Shandong University.

Main research interests: tumor immunology and molecular biology.

In recent years, she has undertaken the youth fund of Shandong Health Department, "The role of APC, hMSH1, hmSH2 genes in the diagnosis and treatment of colon polyps and colon cancer", and the project of Shandong Science and Technology Department, "The molecular mechanism of malignant tumor metastasis", etc. She is now responsible for the research of "Screening of HPV subtypes of viruses related to the pathogenesis of cervical cancer and the mechanism of its down-regulation", and the Shandong Science and Technology project, "The role of differentiated proteins in the diagnosis of colorectal cancer in serum". Differential Proteins in Colorectal Cancer Diagnosis and Metastasis", "Research on the Relationship between HBV Infection and Host MHC-I Class", etc., with a longitudinal research fund of 450,000 RMB. The research on the role of tumor surface and host MHC in the development and metastasis of some solid tumors was recommended by the Ministry of Education of China for the Second Prize of National Scientific and Technological Progress, and the research on the third prize of Shandong Provincial Scientific and Technological Progress and the second prize of Shandong Provincial Medical Science and Technology Innovation Achievement were awarded. He is a member of the editorial committee of the "Eleventh Five-Year" planning textbook of national institutions of higher education "Clinical Laboratory Immunology", deputy editor of "Medical Laboratory and Clinical" of the National Specialty Physician Training Textbook of the Department of Science and Education of the Ministry of Health, and the chief editor of "Modern Laboratory Technology and Quality Control", "Laboratory and Clinical Kidney Disease" and other books, and he has participated in editing six books of "Molecular Immunology and Clinical" and other books. He has also co-edited six books, including Molecular Immunology and Clinics. In recent years, he has published more than 40 academic papers in core journals at home and abroad, and 6 SCI papers, including "Association of human papillomavirus type 16 E7 and HLA class I antigen expression in cervical In 2009, we are going to recruit 2 PhD students, who will be able to work in the hospital laboratory and scientific research institutions.

1. "Research on the screening and mechanism of HPV subtypes related to cervical cancer" National Natural Science Foundation of China, the first (80,000 RMB)

2. "Research on the mechanism of down-regulation of HLA-I molecules on the surface of cell membranes caused by the HPV16 E7 gene" Shandong Provincial Fund for Outstanding Discipline Leaders in Medicine and Health, the first (100,000 RMB)

3. "The role of serum differential protein in the diagnosis of colorectal cancer and in the development of the disease of colorectal cancer. Research on Serum Differential Proteins in the Diagnosis and Metastasis of Colorectal Cancer" Shandong Science and Technology Research Project, the first place (120,000 RMB)

4. "Research on the Application of HLA-I Molecules in Hepatitis B Virus Infected Patients" Shandong International Cooperation Project, the first place (100,000 RMB)

5. "Research on the Mechanisms of Down-regulation of MHC-I Molecules in Cervical Cancer Caused by HPV" Natural Science Foundation of Shandong Province, the first place (50,000 RMB)

6. Fund, the first place (50,000 yuan)

1. Association of human papillomavirus type 16 E7 and HLA class I antigen espression in cervical premalignant and malignant lesions. International journal of Biological Markers 2007,22(2):124-131 (Corresponding author, SCI refereed)

2. Establishment of serum protein pattern for screening colorectal cancer using SELDI-TOF-MS. Experimental Oncology 2006,28(4):282-287 (Corresponding author, SCI reprint)

3. Expression of HLA class I and II on Expression of HLA class I and II on peripheral blood lymphocytes in HBV infection. (First author, SCI)

4. Application of liquid-phase microarray technology to screen human papillomavirus genotypes in high-risk populations in Shandong, Chinese Journal of Epidemiology 2007, 28(5):487-490 (Corresponding author)

5. . Establishment of real-time fluorescence quantitative PCR methodology for the determination of human papillomavirus type 16 E7 gene and its application value in the diagnosis of cervical diseases, Chinese Journal of Laboratory Medicine 2007, 30(10) (Corresponding author)

6. Establishment of HLA-A mRNA methodology for lymphocytes and its application in HBV-infected patients, Chinese Journal of Laboratory Medicine 2006,29( 8): 708-710 (first author)

7. Detection of platelet microparticles, surface membrane glycoprotein IIb-IIIa, and aggregation rate in elderly patients with thrombosis, Chinese Journal of Geriatrics 2004,23(6): 390-392 (first author)

8. Correlation between platelet microparticle detection and the antiplatelet membrane glycoprotein CD62P in ITP patients. Correlation between platelet microparticles and antiplatelet membrane surface glycoprotein CD62P in patients with ITP, Chinese Medical Journal 2003,83(21): 1918-1919 (first author)

Publication of academic writings

1. Modern Laboratory Medicine Technology and Quality Control, Shandong Science and Technology Publishing House, 2004, first editor

2. Tests and Clinical Diagnosis of Renal Diseases, People's Army Medical Press, 2006, first editor

3. First Editor-in-Chief

3. Medical Testing and Clinical Application, People's Health Press, 2008, Deputy Editor-in-Chief

4. Clinical Testing and Immunology, "Eleventh Five-Year Plan" National Planning Teaching Material, Higher Education Press, 2007, Editorial Committee

5. Molecular Immunology and Clinical Practice, Shandong Science and Technology Press, 2003, Editorial Committee

6. Shandong Science and Technology Press, 2003, Editorial Board Member