What are the preparation methods of tablets, and what are their characteristics?

The preparation methods of tablets are direct compression, wet granulation and dry granulation, because the wet method is the most widely used in China, and most of them are relatively pure.

Dry granulation is only used for the wet method can not be solved, such as raw materials are not stable to moisture and heat, the wet method can not control its dissolution, etc., the direct compression of tablets outside of France is more advocated, because of its preparation process is more simple.

By the original drug, filler, adsorbent, binder, lubricant, wetting agent, disintegrating agent, spices, coloring and so on. The material is first crushed, granulated, dried, and then made into tablets with a tablet press, and some are pressed directly into tablets without granulation and drying.

Extended information:

Tablets are developed on the basis of the use of pills, which was created in the 1840s, and by the end of the 19th century with the emergence of the tablet press machinery and continuous improvement, the production and application of tablets have been rapidly developed.

In the last decade or so, there have been major developments in tablet production technology and mechanical equipment, such as boiling granulation, full powder direct compression, semi-film coating, new excipients, new processes, and production linkage.

The research and production of Chinese medicine tablets only began in the 1950s. With the comprehensive research on the chemistry, pharmacology, preparation and clinical aspects of Chinese medicine, the varieties and quantities of Chinese medicine tablets have been increasing, and the process technology has been increasingly improved, and the quality of tablets has been gradually improved.