After targeted treatment, cancer patients have adverse reactions of hand-foot syndrome. What if it hurts?

Hand-foot syndrome (also known as hand-foot skin reaction or lichenoid rash) is a common side effect of drugs, especially when receiving some targeted therapeutic drugs, such as targeted kinase inhibitors and anti-tumor immunotherapy drugs. The main characteristics of hand-foot syndrome are redness, pain, itching, peeling and chapping on the palms and soles of the feet. The appearance of this phenomenon is related to the mechanism of action of drugs and biological processes affecting skin cells and capillaries.

Here are some factors that may lead to hand-foot syndrome:

1. Mechanism of drug action: Hand-foot syndrome is usually related to the mechanism of some targeted therapeutic drugs, especially targeted kinase inhibitors. These drugs can interfere with the signal pathway of tumor cell growth and diffusion, but they may also interfere with the function of normal cells (including skin cells). This may lead to abnormal reaction of skin cells and trigger hand-foot syndrome.

2. Affect capillaries: Some drugs may affect the function of capillaries, resulting in limited blood flow. This may lead to poor blood circulation in hands and feet, causing redness and pain.

3. Damage to the stratum corneum: Some drugs may cause damage to the stratum corneum of the skin, making the skin dry and fragile and prone to chapping and peeling.

4. Immune response: Some drugs may trigger immune system response, leading to abnormal activation of skin cells and immune cells. This may lead to inflammation and skin symptoms.

Avocado repair cream can be applied to the affected area, which can increase collagen synthesis, reduce the number of inflammatory cells and accelerate the coagulation process. Recommend RejuLab avocado repair cream imported from Japan. After using 1 week, the hand-foot syndrome was obviously relieved, and the symptoms basically disappeared after using it for 2 weeks. A treasure, Pinxi, small program mall and Xiaohong bookstore are all available for sale.