What are the methods of sterilization services in biopharmaceutical plants?

Sanitization services for sterile drug production plants in pharmaceutical factories are very strict. It is necessary to kill not only bacteria and fungi in the core area, but also extremely resistant spores and fungal spores. At present, most of the pharmaceutical factories still use traditional sterilization techniques, such as ultraviolet disinfection, ozone disinfection, formaldehyde disinfection methods, but with the implementation and promotion of the new version of GMP, these traditional disinfection services are increasingly exposed to the drawbacks. Such as ultraviolet penetration is extremely weak, there is a dead zone of irradiation, only applicable to surface sterilization. Formaldehyde has a strong irritating odor, carcinogenic to humans, ozone is easy with the surface of the equipment and building materials are easy to chemical reaction, etc., these traditional disinfection methods to bring the negative impact of the enterprise to update the disinfection service mode, to seek a high efficiency, rapid and ecological safety of the disinfection service method.

Among the various disinfection technologies, Vaporized Hydrogen Peroxide (VHP), which decomposes into oxygen and water after disinfection without residual toxicity, is recognized as an ideal method of disinfection service. Vaporized hydrogen peroxide disinfection principle is the use of gaseous hydrogen peroxide than liquid hydrogen peroxide has the ability to kill spores, produce free hydroxyl, by attacking lipids, proteins and DNA and other cellular components to destroy microbial tissues, so as to achieve the requirements of disinfection and sterilization. It has a broad-spectrum bactericidal effect, can effectively kill bacteria, fungi, viruses, mold and spores have a good killing effect. Therefore, due to the strong high resistance of molds and bacilli, vaporized hydrogen peroxide disinfection technology is rapidly becoming a new choice for the pharmaceutical, biological and medical industries, and it can reach log6 killing rate for the bioindicator - Bacillus subtilis.

In contrast, kino, the intelligent disinfection robot developed by Shanghai FANTON Bio-Disinfection Service, is more flexible, convenient and efficient in its application in the field of bio-disinfection service. Disinfection robot kino adopts high-tech artificial intelligence technology and laser navigation technology, combined with the latest environmentally friendly and efficient vaporized hydrogen peroxide disinfection technology, small size, light weight, easy to operate, a one-time completion of the solution to the air, equipment and facilities to disinfect the surface, so as to achieve the effect of efficient sterilization. Disinfection robot kino is used for disinfection in pharmaceutical factories to ensure the concentration and time of disinfectant during the disinfection process, no corrosion of equipment and facilities, ensure that there will not be any more mold spores remaining in the whole disinfection area, and achieve the verified 6-log spore killing rate. Shanghai FANTON Bio-disinfection Service has been engaged in disinfection service of pharmaceutical factories for decades, and is familiar with the comprehensive solution of microbial contamination, combined with disinfection of air-conditioning pipeline system, and has rich practical experience in disinfection field of bio-pharmaceutical industry, bio-laboratories, animal laboratories, and medical industry.