Traditional Culture Encyclopedia - Traditional culture - What is gene sequencing?
What is gene sequencing?
Gene sequencing related products and technologies have developed from laboratory research to clinical application. It can be said that gene sequencing technology is the next technology to change the world. Beginning in the early 1990s, academic circles began to set foot in the "Human Genome Project". The traditional sequencing method is to use optical sequencing technology. Four different bases were labeled with different colors of fluorescence, and then the fluorescence signal was captured by laser light source to obtain the sequence information of the gene to be tested. In the latest gene sequencer, the chip replaces the traditional laser lens and fluorescent dye, and the chip is the sequencer. Through the semiconductor sensor, the instrument can directly detect the ion current generated during DNA replication. When the reagent enters the chip through the integrated fluid channel, the densely distributed reaction holes on the chip immediately become millions of micro-reaction systems. This combination of technologies enables researchers to obtain genetic information in just two hours.
Gene sequencing is just one of the methods of gene detection, also known as gene sequencing, which is an internationally recognized gene detection standard. Gene sequencing is also a well-known non-invasive prenatal genetic test for Down syndrome screening. We only need to collect the peripheral blood of pregnant women, sequence the free DNA (including Patau's free DNA) in the blood, and make a biological analysis of the sequencing results, so as to find out whether there are diseases with abnormal chromosome number in the fetus, including the common 2 1- trisomy syndrome (Down syndrome), 18- trisomy syndrome (Edward syndrome) and/kloc-.
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