Side effects of inactivated vaccines Pros and cons of inactivated vaccines

1 Side effects of inactivated vaccines

Inactivated vaccines, like other vaccines, may have certain side effects after vaccination, and the common side effects of inactivated vaccines are divided into two main categories:

The first is the local side effects at the site of the injection, often manifested as pain, redness, swelling, and hardness at the site of the injection, etc.; the second is the systemic side effects, and the inoculated person may suffer from fatigue, headache, muscle pain, joint pain; sometimes there are also fever and chills. , joint pain; and sometimes fever and chills;.

But these side effects usually appear within 3 days after vaccination, and most of them can be relieved on their own after a few days, so there is no need to worry too much; but for the more serious side effects, you need to report to the relevant vaccination site in time to receive timely treatment.

2 Advantages and disadvantages of inactivated vaccines Advantages

Safe to use, easy to store, no risk of contamination, insensitive to the neutralizing effect of maternal antibodies, easy to make into a combined vaccine or multivalent vaccine.

Disadvantages

Large dose of vaccination, short immunization period, a single route of immunity, mainly to stimulate humoral immunity, can not produce good mucosal immunity.

3 Which is better, inactivated or recombinant

Both are better.

Inactivated vaccine

Inactivated vaccine is the most traditional method of vaccine preparation, but also the most mature method of vaccine preparation; simply put, it is through the injection of artificially inactivated pathogenic microorganisms or their metabolites (antigens), the human body through the recognition of the production of antibodies against the antigens, and once subjected to the invasion of the external specificity of the virus, the immune system to stimulate the production of immune substances (antibodies) Thus, the role of resistance to viral invasion; mature technology, better safety, but the production cycle is longer (more than 60 days), weakened immunogenicity, the need for multiple immunizations and booster immunizations.

Recombinant vaccines

Recombinant vaccines are vaccines produced through the mechanism of recombination in genetics, to solve the problems of traditional vaccines, reduce immunogenicity, improve safety, reduce treatment time, people propose a new SIT method; in fact, no matter which vaccine, after vaccination below the prevention of the new crown effect is better.

4 three shots of the vaccine is better than two shots

There is no clear distinction between the advantages and disadvantages.

The three-shot vaccine and the two-shot vaccine are two different types of vaccines. The biggest difference between the three-shot vaccine and the two-shot vaccine is the difference in process; the three-shot vaccine is a recombinant protein vaccine that requires three shots, and the two-shot vaccine is an inactivated vaccine that requires two shots.

Both vaccines have the same effect and applicability, and their effectiveness and safety are based on reliable clinical trial data, so you can be assured of vaccination; there is no such thing as which one is better, and since vaccination is free for the whole population at the moment, it is enough to be vaccinated according to the vaccine assigned by the region in an orderly manner.