Advantages and disadvantages of genetically engineered antibodies

Genetically engineered antibody advantages: through the modification of genetic engineering technology, it can reduce or even eliminate the human body's rejection reaction to the antibody; genetically engineered antibodies have smaller molecular weights, which can partially reduce the mouse origin of the antibody, and is more conducive to penetrating the blood vessel wall and enter the core of the lesion; prepare new types of antibodies according to the needs of the treatment; can use a variety of expression forms such as prokaryotic cells, eukaryotic cells and plants to express antibody molecules in large quantities, which greatly reduces the cost of production.

Disadvantages of Genetically Engineered Antibodies: Genetically engineered antibodies are experiments that use gene recombination and protein engineering techniques to modify them, and their disadvantages are interference with ecological balance, restriction of genetic diversity, and so on.

Genetic engineering, also known as gene splicing technology and DNA recombination technology, is based on the theory of molecular genetics, molecular biology and microbiology as a means of modern methods, will be different sources of genes according to the pre-designed blueprint, in vitro construction of hybrid DNA molecules, and then imported into the living cells, in order to change the original genetic characteristics of living organisms, to obtain a new variety, the production of new products of the genetic technology. Genetic engineering technology provides a powerful means for the study of the structure and function of genes.