What side effects can epilepsy patients have when taking medicine for a long time?

Side effects of long-term use of epilepsy drugs:

1. Dose-related adverse reactions: such as sedative effect of phenobarbital, dizziness, diplopia and ataxia caused by carbamazepine and phenytoin sodium are all dose-related. This adverse reaction can be alleviated by slowly increasing the dose from a small dose and not exceeding the therapeutic dose recommended in the instructions as much as possible. Where is the base address of epilepsy treatment in Huangshan?

2. Adverse reactions of specific physique: generally appear in the first few weeks of treatment, and have nothing to do with dosage. Some specific adverse physical reactions are rare, but they may be life-threatening. Almost all traditional AEDs have reported specific adverse physical reactions. There are mainly skin damage, severe hepatotoxicity and blood system damage. Lamotrigine and oxcarbazepine have also been reported in new antiepileptic drugs. This kind of adverse reaction is generally mild, and will be relieved soon after stopping the drug. Some critically ill patients need to stop taking drugs immediately and deal with them actively.

3. Long-term adverse reactions: related to cumulative dose. If the patient is given the minimum dose that can control the attack, the drug can be gradually stopped or reduced after several years of no attack, which is helpful to reduce the long-term adverse reactions of AEDs.

4. Teratogenesis: The incidence of deformity in the offspring of epileptic women is about twice that of normal women. There are many reasons for the deformity of offspring, including genetic factors, seizures, taking AEDs and so on. Most researchers believe that the adverse reaction of antiepileptic drugs is the main cause of offspring malformation.