What are the two methods of specimen preparation and fixation

These are physical specimen fixation and chemical specimen fixation.

Extended information:Fixation Fixation allows the material to remain in its original form as long as possible without deterioration. Specimen production process, the first material to be fixed after preservation. Commonly used fixation methods include drying and dipping two kinds of liquid. Immersion specimens, beforehand to use a certain concentration of chemical drug solution as a fixative. The material is dipped and then preserved.

Small animal material, directly placed in the fixative solution for preservation. For large materials, a portion of the fixative is injected into the material first, and then it is placed in the fixative for dipping.

Sample specimen fixation methods are divided into several

Usually there are two methods for sample specimen fixation in general,

that is, physical specimen fixation and chemical specimen fixation method.

For physical specimen fixation is to reflect the use of hot and cold or microwave and so on

physical methods of biological structure and tissue fixation, in the ultrastructure research

Cryogenic fixation and microwave fixation is more commonly used physical fixation methods.

And for chemical specimen fixation is to use a chemical reagent to fix the structural tissues or cells, and this chemical reagent is called

fixative.

It is usually able to chemically bind to macromolecules in cells, mainly proteins,

forming crosslinks to stabilize the protein components, and

also preserving sugars and fats.