Can I change the esc key in dota2?

In the initial interface of DOTA2 client, click the setting button in the upper left corner to enter the DOTA2 setting interface.

2. In the skill bar under "Control", you can customize your own hero skill shortcut. The default skill shortcut is QWEDFR. If the players of DOTA 1 are not used to this shortcut key, they can click the "traditional key" on the upper right to check it, so that the hero's skill shortcut key will be exactly the same as DOTA 1.

In the item bar under "Control", players can also customize their own shortcut keys for the item bar. Players only need to click the button in the settings, and they can modify the shortcut keys of the items themselves.