Auxiliary noun explanation

Adjuvants are nonspecific immune enhancers. When antigens are injected or pre-injected into the body, they can enhance the immune response of the body to antigens or change the types of immune responses.

Adjuvants are substances that can enhance or change the immune response of the body to antigens at the same time or in advance. There are many kinds of adjuvants; Such as aluminum hydroxide adjuvant, Corynebacterium parvum, lipopolysaccharide, cytokine, alum, etc. Freund's complete adjuvant and Freund's incomplete adjuvant are the most commonly used adjuvants in animal experiments.

Extended data

It was not until 1926 that aluminum salt was first used in vaccines, which also proved that "adjuvant" can improve immune persistence, and aluminum salt stood out for more than 60 years.

Followed by adjuvants such as squalene, aluminum complex, liposome, etc. Among them, the most striking is that it is used as a series of adjuvants in vaccines such as influenza, human papillomavirus and herpes zoster. And from the point of view of immunogenicity, they are all directed against their specific antigens.

I have to say that the safety and effectiveness of adjuvants are much higher than decades ago (after all, no one will inject crumbs into your arm), but many people are still speculating about the safety of adjuvants in vaccines in various ways, just because they don't want you to be vaccinated to prevent diseases.

Baidu encyclopedia-assistant