Research method of stability in the process of developing new Chinese medicine

The research methods of stability in the process of developing new Chinese medicine are as follows:

1, determination of stability inspection index

It is very important to determine the stability index in the process of developing new Chinese medicine. This includes investigating the physical, chemical and biological stability of drugs. Physical stability involves the appearance, hardness and brittleness of drugs.

Chemical stability involves the composition content and impurity content of drugs; Biological stability involves the resistance of drugs to microorganisms, bacteria, etc. Through the investigation of these indexes, we can comprehensively evaluate the changes of drugs during storage.

2. Test of influencing factors

Influencing factor test is an important means to evaluate the stability of drugs. This experiment simulates various conditions that drugs may encounter during actual storage and use, such as temperature, humidity and light. To observe the changes of drugs under these conditions. Through the test of influencing factors, the stability of drugs under various conditions can be determined, which provides a basis for the production, storage and use of drugs.

3. Accelerated test and long-term test

Accelerated test is to study the stability of drugs under accelerated conditions. This experiment can accelerate the decomposition and change of drugs by raising the temperature and other conditions, so as to evaluate the stability of drugs in a short time. Long-term trial is a study on the stability of drugs under conditions close to actual use, which can evaluate the stability of drugs in actual use more accurately.

Significance of new drug development of traditional Chinese medicine

1, supplement and expand the resources of traditional Chinese medicine

To develop new Chinese medicine, we can first supplement and expand the resources of Chinese medicine. Due to the limited resources of traditional Chinese medicine and the change of ecological environment, some traditional Chinese medicines can no longer meet the needs of modern medicine. Through the development of new Chinese medicine, we can find and explore new Chinese medicine resources and provide more and better drug choices for clinical treatment.

2. Improve the clinical efficacy.

The development of new Chinese medicine can improve the clinical efficacy. On the basis of traditional Chinese medicine theory, using modern science and technology and methods, researchers can conduct in-depth research on certain diseases and discover new treatment strategies and drugs. These new drugs may have stronger curative effect, lower side effects and better administration methods, thus providing more effective means for clinical treatment.

3. Promote the modernization of traditional Chinese medicine.

The development of new Chinese medicine is an important part of the modernization of Chinese medicine. The development of new Chinese medicine can promote the standardization, modernization and internationalization of Chinese medicine. At the same time, scientific research and technological innovation in the process of new drug development can also promote the development and progress in the field of traditional Chinese medicine and enhance the international status and influence of traditional Chinese medicine.