What are the advantages of solid phase extraction in treating biological samples?

Solid phase extraction is mainly the pretreatment before sample analysis, that is, purification, concentration and enrichment, phase inversion and online derivation. 1: adsorption of pharmaceutical ingredients, single fixation, suitable for large-scale batch purification operation.

2. Emulsification is a common phenomenon in LLE. Once emulsification occurs in the extraction process, it will seriously affect the reproducibility of the results, but it does not exist in SPE.

3. The main disadvantage of 3.LLE is that the recovery rate depends largely on the operator's proficiency in this technology, while SPE extracts analytes based on the interaction between the functional groups of analytes and the functional groups of SPE column stationary phase fillers. This method has good reproducibility, is easy to transfer between laboratories and is beneficial to standardization.

4. Solid phase extraction has the advantages of strong selectivity, short separation time and less use of organic solvents.

Its advantages are mainly:

1 can extract the tested substance more thoroughly.

2. The efficiency of separating the measured object from the interfering object is higher.

3 reduce the consumption of organic solvents

4. It is easy to collect all the measured parts.

5 manual operation is more convenient

6 can remove particles