Do you need a liver puncture biopsy for fatty liver

? A liver puncture biopsy is the most accurate test to check the extent of liver damage, although not many liver puncture biopsies are performed for fatty liver these days. Many people with fatty liver think that liver puncture biopsy is not necessary for fatty liver. In fact, if you want a more accurate test, it is best to have a liver puncture biopsy. Many patients with fatty liver just have blood biochemistry tests, or imaging tests, although these are important for the diagnosis of fatty liver, but liver puncture biopsy is the gold standard for the diagnosis of fatty liver. 1、Why should fatty liver do liver puncture examination Liver puncture is the short form of liver puncture biopsy wood, which is based on the principle of negative pressure suction, using rapid puncture method, extracting a small amount of liver tissue from the liver, and then doing pathological histology, immunohistochemistry and other staining after processing, directly observing the changes in the morphology of liver tissues and immune factors under the microscope, and then combining with the clinical information to make a diagnosis of the condition. Meanwhile, in addition to fatty liver, including hepatitis B and cirrhosis, it is better to have liver tissue biopsy. If the metabolism of liver fat is impaired, the balance is imbalanced, resulting in the accumulation of fat in the liver, if its weight exceeds 5% of the weight of the liver (wet weight), or if there is more than 30% of the liver weight (wet weight), then the liver tissue biopsy should be performed. If the weight of the fat is more than 5% of the liver weight (wet weight), or if more than 30% of the liver has steatosis and it is diffusely distributed throughout the liver, it is called fatty liver. The diagnostic value of liver puncture is much higher than that of blood biochemistry and imaging examination, and it is the only method to confirm the diagnosis of fatty liver, determine steatohepatitis and liver fibrosis, and it can also clarify the degree and pathological type of fatty liver, and whether there are symptoms of combined steatohepatitis and liver fibrosis, and it can suggest the cause of fatty liver as well as understand the healing situation. 2、Fatty liver biopsy can be divided into two types: small vesicular and large vesicular according to the diameter of intracellular ester droplets in the liver; according to the degree of fatty degeneration of hepatocytes under HE staining light microscope of liver biopsy tissue, fatty liver can be divided into mild, moderate and severe. 3, liver puncture biopsy precautions Because the operation of liver biopsy is traumatic, patients are generally difficult to accept. In fact, since 1883, Paul Ehrlicl of Germany first applied liver biopsy to the clinic, there has been a history of more than 100 years, with the continuous improvement of puncture instruments and operation methods, simplification of steps, shortening of time, as well as the improvement of safety, liver biopsy is also becoming more and more popular. Patients usually need to undergo local anesthesia, use negative pressure suction puncture technology, and transcutaneous puncture under the positioning and guidance of ultrasound and CT, which is convenient, safe and has a high success rate. Contraindications to liver puncture Not all patients can undergo liver puncture, patients need to undergo a series of tests before liver puncture, such as PT, platelet count and coagulation time, ultrasound or CT, etc., to understand the purpose and method of liver puncture, as well as possible complications, etc. Patients should be informed of the purpose of liver puncture, the method of liver puncture and the possible complications. If blood pressure is found to be high after liver puncture, the patient will be able to have a good blood pressure. After liver puncture, if you find that the blood pressure drops, headache and panic, the pulse rate increases, then it is necessary to immediately find that the blood pressure drops, headache and panic. If you notice a drop in blood pressure, panic in the head, or a rapid pulse rate, you should consult a doctor immediately to avoid delaying your condition. After liver puncture, some patients may have transient pain in the liver area or pain at the site of liver puncture, but the reaction is mild and does not require treatment, and can be relieved after 24 hours.