What are the preparation methods of tablets? What drugs are suitable for each method?

The preparation methods of tablets include direct compression, wet granulation and dry granulation, because wet granulation is the most widely used method in China, and most of them are skilled.

Dry granulation is only used in wet method, for example, raw materials are unstable to damp heat, and wet method cannot control its dissolution. Direct compression method is advocated abroad because of its simple preparation process.

It consists of raw materials, fillers, adsorbents, adhesives, lubricants, wetting agents, disintegrants, spices, pigments, etc. First, the raw materials are crushed, granulated and dried, and then pressed into tablets by a tablet press, or some of them are directly pressed into tablets without granulation and drying.

Extended data:

Pills were developed on the basis of the first use of pills in11940s. By the end of 19, with the appearance and continuous improvement of tablet press, the production and application of tablets developed rapidly.

In recent ten years, tablet production technology and mechanical equipment have also made great progress, such as boiling granulation, full powder direct compression, semi-film coating, new excipients, new technology and production linkage.

The research and production of traditional Chinese medicine tablets began in 1950s. With the comprehensive study of chemistry, pharmacology, preparation and clinic of traditional Chinese medicine, the variety and quantity of Chinese medicine tablets are increasing, the technology is improving day by day, and the quality of tablets is also improving step by step.