Traditional Culture Encyclopedia - Traditional festivals - What are the abnormal skin changes when liver cancer occurs?

What are the abnormal skin changes when liver cancer occurs?

In the following, Dr. Long will analyze and summarize several skin manifestations related to liver cancer:

1. Skin chaffing rash

Mainly manifested as round or oval chaffing rash with clear boundary and patchy lesions accompanied by scales, which suggests that there may be liver cancer, and it is a kind of useful diagnostic sign, especially for people who have dark skin color. Chronic hepatitis B virus infection.

2. Delayed Cutaneous Porphyria

Delayed Cutaneous Porphyria is a rare skin disorder that is characterized by erythema, blisters, and vesicles that may become hemorrhagic after exposure to sunlight or minor trauma to the skin, and should be noted in patients with chronic hepatitis C.

Porphyria of the skin is a rare skin disorder that is characterized by erythema, blisters, and vesicles that may become hemorrhagic after exposure to sunlight or minor trauma to the skin.

3. Multiple seborrheic keratoses

Also known as Lesar-Trelat's sign, the patient's lesions are characterized by an eczema-like basal inflammatory reaction, which may be accompanied by skin tags and acanthosis nigricans.

4. Pemphigus

Deciduous pemphigoid is an epidermal blistering dermatosis similar to pemphigus vulgaris, which seldom involves mucous membranes, and the blisters are often superficially vesiculated with erythema, scales, and scabs similar to those of severe seborrheic dermatitis.

5. Dermatomyositis

Dermatomyositis is a disease with a variety of manifestations. Dermatomyositis associated with hepatocellular carcinoma is long manifested as scaly violet papules on the extensor side of the hand, violet patches of skin around the eyes, heterochromatic patches of skin in the lighted areas, as well as plaques, squamous plaques on the scalp and inner thighs, or peri-nail capillary dilatation and skin roughness.

Q&A most attentive, reliable Dr. Long!

Life Road public welfare health that the skin changes are more recognized is the liver palm, spider nevus, abdominal vein exposure, some will have skin jaundice. Liver cancer is the "king of cancer", the human body sugar, protein, fat three basic metabolic substances are completed in the liver. It is also a detoxification organ, and vitamin and hormone metabolism is also carried out in the liver, so liver cancer is too dangerous. You can't just look at the abnormal changes in the skin, because the liver carries out the important biochemical reactions mentioned above, and the discovery is advanced, so it is good to pay attention to all aspects of observation.

Chinese medicine believes that the liver is the main detachment of blood, if there is emotional irritability, breast, abdomen, ribs and other places uncomfortable, may be related to the liver function changes, the liver is the main tendon, if you feel the tendon flexion and extension of unfavorable, muscle sometimes tremor, etc., but also some of the relationship with the liver. That is to say, we usually pay attention to some, do not wait for the liver is too tired, or go to the test when the liver function problems, then start to adjust the attention, so as to avoid liver damage. Cancer occurs in many years when the long-term accumulation of lumps, usually pay attention to avoid the occurrence of major diseases.

Life Road public welfare health advice, usually pay attention to less alcohol or do not drink, every day regular life, sleep enough, moderate exercise. Keep your mood relaxed, and don't eat too much fat, sweet, thick and greasy food in your diet. In short, you should pay attention to your own maintenance.

Skin abnormalities that liver cancer may have include:

The most typical ones are liver palm and spider mole. Liver palms are characterized by flaky congestion or red spots or plaques on the skin at the interstices of the thumb and the root of the little finger of the palm of the hand, which become pale white after pressure is put on them. Spider nevus is a nevus formed by the expansion of small arterial branches of the skin, with a center point, surrounded by small blood vessel branches in radial shape, which is called spider nevus because of its spider-like shape, and usually occurs in the area where the superior vena cava is distributed (face, neck and upper chest and shoulder, etc.). In fact, they are the manifestation of hepatitis cirrhosis, not the unique manifestation of liver cancer, so the appearance of this lesion can only say that the manifestation of liver abnormalities, cirrhosis, but not liver cancer, this has to be further examined, a lot of liver cancer does have hepatitis cirrhosis, but it is not necessarily, so it is not necessarily the manifestation of the liver palms and spider naevi.

Hepatocellular carcinoma may also have itching, which is due to biliary stasis caused by hepatocellular carcinoma. And also due to bile stasis, bilirubin is elevated and there will be manifestation of jaundice, which is the manifestation of yellow coloration of skin or mucous membrane.

Liver diseases, including liver cancer, have developed to a certain extent, there will be the so-called liver disease face, which can also be considered a skin manifestation, manifested as the patient's facial skin pigmentation, loss of luster, gray or even gray-black.

When it comes to liver cancer, this kind of cancer is actually very scary, and there is almost no way to cure it except for liver transplantation. Liver cancer is a kind of malignant tumor that occurs in hepatocytes and intrahepatic bile duct cells mainly due to various reasons, and so far, the pathogenesis of liver cancer is not clear, but there are a lot of triggering factors.

The most common predisposing factor of liver cancer is hepatitis B virus, which is mainly due to the abnormal gene expression of hepatocyte DNA and carcinogenesis. The most common predisposing factor for liver cancer is the hepatitis B virus, which is caused by abnormal gene expression due to hepatocyte DNA, and cirrhosis, which is caused by atypical hyperplasia in the liver after liver cell damage. In addition to this, there are cholestasis, excessive alcohol, liver stasis, aflatoxin infection, chemical poisoning and other factors triggered.

Liver cancer is more insidious, and the early symptoms are not obvious, but in the middle and late stages, it will gradually appear right upper abdominal (liver area) pain, and there is a feeling of abdominal distension and pain in the back of the right shoulder, and the rupture of the liver cancer nodule will appear severe persistent abdominal pain, and some pain relievers have no effect, and it will lead to the food loss, nausea and vomiting, nutritional malabsorption, leading to emaciation, fatigue, poor nutrition and generalized infections, etc. And it will also reach to the symptoms of liver cancer. The symptoms such as nausea and vomiting, malabsorption of nutrients leading to weight loss, fatigue and poor nutrition, systemic infections, etc., and the symptoms of various tissues and organs after the cancer cells metastasize at night.

However, there are also symptoms in the skin after liver cancer appears, which are mainly as follows!

1, itchy skin, because liver cancer leads to abnormal operation of bile in the liver, but itchy skin is not necessarily liver cancer, but if people with hepatitis and other people have unexplained itchy skin, and use anti-itching medicines without any effect, they should be alert to liver cancer. Many cancers with high degree of malignancy will lead to the appearance of rashes and erythema on the skin mucosa of the body surface.

2, spider nevus and liver palms appear in the palm of the hand, liver disease patients appear liver palms and spider nevus of the same reason, are because of liver dysfunction, can not deal with estrogen, resulting in excessive estrogen effect on small arteries, so that the expansion caused by. In addition, due to the retention of a certain vasodilator substance in the blood, so that the contraction function of the vascular sphincter cells is reduced, there is more blood through the micro-arteries, and increase the pressure on the wall of the blood vessel, so that the blood vessel bends, coils and extends with the region of the lowest skin tension, and eventually the formation of the spider nevus.

3. Yellowing of skin, mainly in face and iris, mainly due to abnormal liver function caused by hepatocellular carcinoma, which makes serum bilirubin rise in blood vessels, and yellowing of skin and iris occurs, and hormonal abnormality leads to grayish face.

Hepatocellular carcinoma is one of the common malignant tumors in China, with high degree of malignancy, rapid progress and great harm. And in liver cancer patients, the skin will also show abnormal changes.

Causes of Liver Cancer

Liver cancer is mostly transformed from chronic liver disease. There are many causes of liver cancer, the most common cause in our country is hepatitis B virus infection, in addition to hepatitis C virus infection, alcoholism, fatty liver, eating moldy food, chemical drugs, inherited metabolic liver disease and so on may lead to liver cancer.

The "specific functions" of liver cancer cells

Liver cancer cells have many functions that normal liver cells do not have.

1. Unlimited growth and division: One of the characteristics of cancer cells different from normal cells in human body is that their growth is unrestricted, as long as human life exists, the growth of cancer cells will not stop.

2. Predator of human nutrition: This is another important feature of cancer cells. It can build up its own arterial blood vessels and use them as its own nutrient channels. In order to satisfy the need of its own crazy growth, it draws nutrients greatly, while other tissues and organs of the human body show lack of nutrients.

3. Savage invader: This is another important characteristic of cancer cells. It not only grows by itself, but also invades other tissues and organs. For example, it directly infiltrates the neighboring tissues and organs, and it can also invade the tissues and organs far away from itself through lymph and blood long-distance running.

Skin manifestations of liver cancer patients

As the saying goes, the wild goose leaves its voice and the wind leaves its trail. There are traces to be found in everything, there are internal and external patterns, and diseases are no exception.

The liver is the first human gland, with synthesis, metabolism, secretion, regulation, transportation and other functions, also known as the human body's "chemical factory".

When liver cancer occurs in human body, due to the small size of liver cancer in the early stage, the impact on human body is not big, and it may not be obvious, but with the development of liver cancer, the damage to the liver is aggravated, which leads to the lowering of liver function and abnormal changes, and the human body's appearance will also change accordingly.

1. Facial skin becomes dark and lusterless: Due to the decline of liver function, the interpretation function of liver decreases, and the endotoxin of human body increases, which is manifested as darkness and lusterlessness in the face, which is called the appearance of slow liver disease.

2. Formation of liver palms and spider moles:

When liver cancer is in the advanced stage, liver cancer cells occupy half of the body, or even more, and there is very little normal liver tissue, the inactivation ability of the liver decreases, and the estrogen in the body increases, which is manifested as a spider mole and liver palms on the skin of the human body.

3. Abdominal wall "green veins" are revealed: Liver cancer can lead to abnormal changes in the structure of the liver, and the blood through the liver is blocked, resulting in portal hypertension. Due to portal hypertension, the blood that passes through the liver is diverted to the abdominal wall veins, and the abdominal wall veins are one of them. Due to the increase in blood, the abdominal wall veins are exposed, commonly known as "veins", which are actually varicose veins.

4. Yellow color of skin and sclera: As we all know, liver is an important organ for bilirubin synthesis and metabolism, when bilirubin synthesis and metabolism is impaired in liver cancer, bilirubin in the body will be elevated, which will lead to yellow color of skin and sclera, and when bile ducts are compressed by the lumps, bilirubin will be more obvious, which is called severe yellow color of skin and sclera. We call it severe yellowing of skin and sclera.

5. Lower limb edema, depression of pressure: The liver has many functions, one of which is to synthesize albumin. When albumin drops in the body, it often indicates serious liver damage. This is often the case in advanced stages of liver cancer. As a result of hypoalbuminemia, the osmotic pressure of the blood decreases and the water in the blood leaks out of the surrounding tissues. Water lives low, so it first manifests as lower extremity edema.

Although the above skin manifestations are not unique to liver cancer patients, but if the above skin manifestations occur in liver cancer patients, it often indicates that liver cancer has already reached the advanced stage, and the condition is very serious. Of course, besides skin manifestations, there are also pain in the liver area, emaciation and so on.

How to Prevent Liver Cancer and Early Detection of Liver Cancer

Once patients with liver cancer have abnormal feeling, it is often in the late stage of the disease, and the best time for treatment is missed. Therefore, it is of great significance to prevent liver cancer and for liver cancer. Early detection, early diagnosis and early treatment can achieve the best effect and even the goal of cure.

1. For the high-risk group of liver cancer, that is, the group of people who are prone to liver cancer, it is necessary to actively treat the primary disease. For example, hepatitis B and C patients should be given antiviral, hepatoprotective and hepatoprotective treatments to reduce the possibility of hepatocellular carcinoma.

2. Change the bad behavior of injury. Eat more fresh fruits and vegetables, do not eat greasy, salted, fried, moldy food; develop a good work schedule, do not stay up all night; quit smoking, quit drinking; peace of mind; appropriate aerobic exercise, reduce body weight.

3. Go to the hospital for regular screening. People at high risk of liver cancer archipelago 3~6 months to the hospital for liver function, alpha-fetoprotein, ultrasound, CT examination. Small liver cancers can be found.

Cirrhosis decompensation stage or liver cancer occurs, due to liver function decline, endocrine disorders, the whole body will appear a variety of symptoms, which is more typical of the abnormal changes in the skin. Below I'll learn about it with you.

What are the abnormal skin changes when liver cancer occurs?

1. Darkening and dullness of face: For patients with liver disease, when liver function decreases significantly, liver disease face will appear, which is manifested as dark and dull face and rough and lusterless skin. Especially around the eyes is more obvious, a little like dark circles.

2. Yellowing of the skin and sclera: Yellowing of the skin and sclera is caused by a decrease in the liver's ability to metabolize bilirubin, and the level of indirect bilirubin in the blood rises, causing jaundice. Due to the deposition of bile salts in the skin, it causes itching.

3. Spider nevus of liver palms: The redness of the liver palms at the intersection of the big and small fishes, as well as the spider nevus of the spider-like shape, are all caused by the abnormal metabolism of estrogen by the liver. It is a typical manifestation of the decline in liver function.

Liver cancer is hard to be found in the early stage, and because it has no pain nerves, it is called "silent cancer king". In fact, when liver cancer occurs, there will be abnormalities in the body and great changes in the skin:

Long-term severe insomnia. If a person can not sleep properly from 1 to 3 pm, it must be taken seriously. Because 1 to 3 pm is the liver meridian qi and blood flow is the most vigorous time, but also the liver is the most busy time. A large amount of blood in the body will flow into the liver, the liver for detoxification. If you can't sleep during this time, it will definitely affect the detoxification function of the liver, making the toxins stay in the liver and planting the seeds for the formation of liver cancer.

Emotional disorders . Under normal circumstances, because the liver has the function of regulating the qi of the whole body, so when the mood is normal and comfortable, the body's qi and blood will proceed in a peaceful and orderly manner, and will not get sick. If a person is angry for a long time, sullen, sentimental, sad and wanting to cry, etc., it is easy to make the liver qi stagnation, resulting in stagnation of liver blood, which will induce liver cancer in the long term.

There are unexplained red dots on the skin of the body, and the red dots are dispersed blood, which may be "spider nevi". It is associated with cirrhosis of the liver and liver cancer.

A dark red change in the skin of the palm of the hand. Normally, the body's blood flows into the liver from 1:00 to 3:00 in the morning, and this blood is of good quality and without any problems. The liver will then detoxify the blood very smoothly during this time period so that the blood flows into the heart. In this case, our palms are pink in color. If the liver grows a tumor or cirrhosis, etc., the person will definitely wake up suddenly at 1:00 or so, and can no longer sleep, and a large amount of blood in the body during this time period will be due to the tumor or cirrhosis in the liver, etc., and the space will become smaller, and a large amount of blood can not be stored, and it will be too late to detoxify the blood, and carry out the detoxification in the way of fast in-feeding and fast out-feeding, and the toxins will flow into the heart along with the blood, resulting in the blood to become darker, and accumulating in the palms of the hands over a long period of time, and it will The dark red color changes, this palm to be extra careful.

Swelling of the lower limbs of the human body, liver cancer ascites, increasing the pain of patients, and in serious cases, life-threatening.

Late liver cancer will have bleeding tendency, and the skin will have petechiae.

To sum up, when liver cancer is going to happen, the body will send out distress signals to us. Therefore, once the body appears abnormal, it should be timely adjusted so that the disease will not develop further. In our daily life, we should keep our mood happy, live with a smile, eat healthy and reasonable diet, and never consume moldy things, such as melon seeds, peanuts, grains, etc. , because these things contain aflatoxin, which is a carcinogen. Ensure adequate sleep time, appropriate exercise, have a healthy life!

Hello! I'm @ForestDoctorXiangzi and I'm here to answer the question of what are the abnormal changes in the skin when liver cancer occurs? I'm here to answer the question of what are the abnormal changes in the skin when liver cancer occurs?

The modern medical diagnosis is to see, touch, knock and listen; the traditional medical diagnosis is to hope, smell, ask and cut. No matter Chinese or Western medicine diagnosis, inspection or observation is put in the first place, which is to observe and analyze the condition through the patient's external performance.

The Yellow Emperor's Classic of Internal Medicine (HECI) has the saying that "if there is something inside the body, it must be seen outside the body," meaning that there must be an external change in the human body's internal pathology.

@ForestDoctorCheungZi

For example, if you see a patient with a deficiency of qi and blood, just by "looking at the words", such as: face, lips, nail beds, pale color, less breath and lazy speech, fatigue, expression of indifference, low voice can be judged to exist in the person of qi and blood deficiency.

The doctor has been engaged in internal medicine for decades, and has seen many patients with liver disease will appear a variety of skin abnormalities, especially liver cancer patients' skin changes are more common, now one by one as follows.

I. Jaundice

Jaundice usually occurs in the late stage of liver cancer, which can be caused by damage of liver cells, or due to the pressure of cancer mass or invasion of bile ducts near the hepatic valve, or due to the obstruction of biliary tract caused by the dislodgment of cancerous tissues and blood clots.

Second, hyperpigmentation

Patients with liver disease have metabolic disorders, endocrine disorders, and increased melanin in the basal layer of the epidermis, resulting in deepening of the skin color. The pigmentation is deeper in the exposed part of the body as well as around the nipples, armpits, reproductive organs, joints and anus.

The hyperpigmentation of the cheeks in patients with liver disease is also known as "liver spots".

Spider nevus is a vascular nevus formed by the branching expansion of the end of the small arteries in the skin, which resembles a spider, so it is called spider nevus.

Spider nevus occurs in the area of superior vena cava, such as the face, neck, back of the hands, upper arms, chest and shoulders.

Spider nevi vary in size from the head of a hatpin to several centimeters in diameter. When examined, the center of the nevus is pressed with a fingertip or a matchstick, and its radial network of small blood vessels fades when pressed, and reappears after the pressure is removed.

However, the presence of one, two or several spider naevi in some people does not necessarily mean that they have liver disease. It can also occur in healthy women during pregnancy.

Clinical findings, many patients with liver disease, in the palms of the big and small fish often red, pressure faded color, called liver palm. The pathogenesis of liver palm is the same as spider nevus.

Fourth, warts

Warts are caused by human papillomavirus (HPV) infection, can be malignant, common warts, metatarsal warts, flat warts and condyloma acuminatum. Different clinical types are caused by different types of HPV, and humans are the only host for this virus.

Warts are transmitted by direct contact and occasionally indirectly through contaminants. Skin trauma is an important factor in contracting the virus.

The occurrence and regression of warts and the body's immune function have a certain relationship, and cellular immunity has a major role in the defense mechanism of warts, immunodeficient people on the incidence of warts is higher than normal people.

Warts appear on the skin of patients with liver cancer, mostly caused by viral infections due to a decline in the body's immunity.

Warts can appear on the neck, back, upper and lower limbs, and genitals or around the anus.

These are the answers to your questions from @DrForestCheungZi, and I hope you find them helpful.

Tips: Pictures from the web

1, itchy skin

Of course, it is ruled out because of the dry weather, allergies and other factors, if it is a persistent itch, and with the use of medication has not been better, should be taken seriously.

2, dark skin

For example, the face, forehead and other body skin color black, dark, more suggestive of the organs of the problem, may be the kidneys, liver, should be timely to do the relevant examination.

3, skin moles

Spider-like red moles, usually distributed in the abdomen or around the navel, the surface looks like a spider, so named spider moles.

4, yellow skin

General tips and liver metabolism, because the liver will secrete bile, if abnormal secretion, the bile ducts secretion to the whole body, will be yellow skin, so the appearance of the appearance of yellow skin, medical generally known as "jaundice.

How to prevent liver cancer?

Prevent Hepatitis B

Get vaccinated against Hepatitis B. If you are infected with Hepatitis B, you should receive treatment as soon as possible;

Don't eat spoiled food

Keep food at home, and don't consume it if you find it spoiled or mildewed;

Take selenium supplementation

Take selenium polysaccharide, selenium-enriched yeast, and so on, and eat fresh vegetables and fruits; eat some fresh vegetables and fruits; and eat some selenium-rich yeast. Eat some fresh vegetables and fruits;

Regular body checkups

Regular body checkups can help you understand your health condition in time.

The human body is a whole, the skin and the whole body has a close connection. Many systemic diseases can be reflected in the skin. When the liver is diseased, it can affect the synthesis and excretion of the combination or regulatory mechanisms, causing changes in the structure and function of the skin. Liver cancer can also cause skin changes. Before answering the question, we would like to remind you that the following symptoms are not diagnostic of liver cancer, they are only clues that suggest liver cancer, and we should not take them lightly! The real diagnosis of liver cancer needs to be made by a specialist with the help of ultrasound, CT, pathology and histology and other auxiliary examinations.

When the following 5 abnormalities appear on the skin, it is possible that the cancer cells have taken root in the liver:

1. Itching

When the cancer cells grow wildly and block the bile ducts in the liver, leading to the accumulation of bile, the patient may have itchy skin. This is due to the fact that when the bile is stagnant, the bile acid salts in the bile combined with bilirubin return to the blood and flow to the whole body with the blood circulation. The bile acid salts are deposited in the skin, stimulating the sensory nerve endings in the skin and causing the patient to feel itchy skin all over the body.

2. Liver disease face

Many liver diseases have liver disease face, including liver cancer. It is mainly manifested as the patients' facial skin, especially the skin around the eye orbits is hyperpigmented, the skin loses luster, and the whole facial skin is gray or even gray-black.

3. Yellowing of the skin

Yellowing of the skin is called jaundice in medicine, which is mainly the yellowing of the skin and mucous membranes. The first characteristic is the yellow color of the white part of the eyes, and with the development of the disease, the skin of the whole body will become dark yellow or yellowish brown. The cause is the same as itchy skin, but also due to elevated bilirubin in the blood.

4. Spider nevus

It is a red spot with small intertwined blood vessels, a central artery in the middle of the red spot, and a pale halo around the outside of the red spot, from the size of a pinhead up to 50px, and the whole nevus looks like a spider and is named so. Large spider nevi can be seen or felt pulsating, especially when compressed with a slide. Spider nevi are mainly found on the upper chest, forearms, hands and face.

5. Liver palms

Liver palms will appear when liver cancer causes liver function damage. It is mainly manifested as pink spots or patches on both sides of the palms of both hands, including the big and small piriformis muscles and the palm surface of fingertips, with the color of cinnabar, which can be changed to white immediately after pressure, and then red soon after no pressure, while the color of the palms is normal. The whole palm of the hand seems to be the color of the periphery reddish, the palm of the white.

In addition to hepatocellular carcinoma, these skin lesions above will have the same or similar performance in chronic viral hepatitis, cirrhosis, liver failure and so on. Therefore, when one of the above changes occurs in the skin, the liver may have developed problems, please make sure to go to the hospital in time for early detection and treatment.

  • Related articles

copyright 2024 Traditional Culture Encyclopedia All rights reserved