What disease is aspirin suitable for?

Aspirin is a commonly used drug with antipyretic and analgesic effects. Its chemical name is acetylsalicylic acid. With the development of modern medicine, in recent years, due to the development of science, it has been found that it has many new pharmacological effects and is closely related to senile diseases. Can prevent cardiovascular and cerebrovascular diseases: the preventive effect of taking small doses of enteric-coated aspirin on myocardial infarction and cerebral thrombosis is certain. 2. Prevention and treatment of senile stroke and Alzheimer's Harmo's disease: Taking aspirin to treat senile stroke and Alzheimer's Harmo's disease can restore consciousness to 17%-20% every year, and it is not easy to relapse. 3. Enhance the body's immunity: Scientists point out that aspirin can promote the production of immune molecules-interferon and interleukin-1. 4. Anti-aging effect: Aspirin can keep the elasticity of human corneal tissue, because aspirin can inhibit the formation of glycogen in corneal tissue, so it can delay the aging process of cornea. 5. Prevention of colorectal cancer: A survey conducted by the American Cancer Society in 50 states and Washington, D.C. showed that the incidence of colon cancer in aspirin group was lower than that in non-aspirin group by more than 40%. 6. Prevention and treatment of diabetes: According to the literature, taking aspirin daily can reduce the occurrence of diabetic microvascular complications, which is due to aspirin's anti-platelet aggregation and anti-thrombosis effects. Aspirin can also stimulate insulin secretion, so it has a hypoglycemic effect. In addition, aspirin has some functions, such as inhibiting the side effects of prostaglandin, lowering blood pressure and protecting fetus. In terms of dosage, it is generally appropriate to take enteric-coated aspirin 100 mg every day; It is best to take it before 7 am. Because platelet aggregation gradually increases and coagulation function is enhanced after getting up in the morning, it is a dangerous moment for cardiovascular and cerebrovascular diseases, so take medicine as soon as possible after getting up in the morning. However, those with gastric ulcer disease and tendency of gastric bleeding should be treated with caution and under the guidance of a doctor. Children \ pregnant women should not take aspirin. Anticoagulation: After aspirin enters the circulatory system, it can be used as the thermoregulatory center of hypothalamus. This center will monitor the temperature of blood and trigger the body to generate heat or dissipate heat. Therefore, aspirin has the effect of reducing fever. It can also cause sweating, hair follicle erection and, most importantly, vasoconstriction or dilation. Anti-inflammatory: Aspirin is often used to treat rheumatism and reduce inflammatory reaction. The concentration of prostaglandin in the blood of patients with rheumatoid arthritis is much higher than that of normal people, thus changing the synovial fluid (left picture). Aspirin inhibits prostaglandin synthesis, thus reducing inflammation and pain. Antipyretic: Aspirin acts on platelets, reducing blood coagulation ability, so aspirin should not be used one week before operation. But it is effective for thrombosis caused by coagulation. The left picture shows the coagulation phenomenon after vascular bleeding. Aspirin is still a widely used and effective drug. The function of aspirin in human body is anticoagulation: after aspirin enters the circulatory system, it can be used as the thermoregulatory center in hypothalamus. This center will monitor the temperature of blood and trigger the body to generate heat or dissipate heat. Therefore, aspirin has the effect of reducing fever. It can also cause sweating, hair follicle erection and, most importantly, vasoconstriction or dilation. Anti-inflammatory: Aspirin is often used to treat rheumatism and reduce inflammatory reaction. The concentration of prostaglandin in the blood of patients with rheumatoid arthritis is much higher than that of normal people, thus changing the synovial fluid (left picture). Aspirin inhibits prostaglandin synthesis, thus reducing inflammation and pain. Antipyretic: Aspirin acts on platelets, reducing blood coagulation ability, so aspirin should not be used one week before operation. But it is effective for thrombosis caused by coagulation. The left picture shows the coagulation phenomenon after vascular bleeding. Anticoagulation: After aspirin enters the circulatory system, it can be used as the thermoregulatory center of hypothalamus. This center will monitor the temperature of blood and trigger the body to generate heat or dissipate heat. Therefore, aspirin has the effect of reducing fever. It can also cause sweating, hair follicle erection and, most importantly, vasoconstriction or dilation. Anti-inflammatory: Aspirin is often used to treat rheumatism and reduce inflammatory reaction. The concentration of prostaglandin in the blood of patients with rheumatoid arthritis is much higher than that of normal people, thus changing the synovial fluid (left picture). Aspirin inhibits prostaglandin synthesis, thus reducing inflammation and pain. Antipyretic: Aspirin acts on platelets, reducing blood coagulation ability, so aspirin should not be used one week before operation. But it is effective for thrombosis caused by coagulation. The left picture shows the coagulation phenomenon after vascular bleeding. Proper use of aspirin gold aspirin is a famous traditional antipyretic, analgesic and anti-inflammatory drug. Besides antipyretic and anti-rheumatism, it also has obvious anti-platelet aggregation effect. Because of its low price and reliable function, it is widely used in the prevention and treatment of cardiovascular and cerebrovascular diseases. Therefore, people pay more and more attention to how to use aspirin correctly and reasonably, maximize its benefits and reduce its side effects. The metabolism of aspirin in the body Aspirin is easily absorbed after oral administration, and it is rapidly decomposed into free salicylic acid in the body, which is mainly metabolized in the liver and excreted by the kidney, and its drug half-life is about 4 hours. When combined with sodium bicarbonate, the excretion of free drugs increased, the blood drug concentration decreased and the drug action time shortened. How to use aspirin People will have some questions when taking aspirin, such as: Who is not suitable for using aspirin? Is there a risk of bleeding when taking aspirin? What dose is appropriate? When is the best time to take medicine in a day? Who is suitable to take aspirin can be divided into the following three situations according to the patient's condition. One is to take it. These people have a history of heart disease or have been diagnosed with cardiovascular diseases, including angina pectoris and myocardial infarction, coronary artery bypass surgery or interventional therapy, stroke and other vascular occlusive diseases, regardless of age, sex, hypertension or diabetes. The second is that you can take it. The situation of this group of people is more complicated. They use aspirin mainly to prevent colon cancer and Alzheimer's disease. In this case, the pros and cons must be weighed. Because, if it is not used well, it will lead to other diseases, but it will not be worth the loss. The last group should not take aspirin. How much dose is appropriate is quite different from the recommended dose in the past, which makes people feel at a loss. This is because there is no experimental instrument to detect the platelet inhibition ability of aspirin in clinic. Many conclusions come from the personal experience of observers. Some people think that aspirin has an anti-platelet aggregation effect in the range of 5mg ~ 100mg, and the risk of bleeding increases when it exceeds 325mg or 500mg. For most patients, oral low-dose aspirin 40 ~ 300mg/ day can play an anti-platelet aggregation and anti-thrombosis role. Generally speaking, most people can get better anti-platelet aggregation effect by taking 75 mg aspirin every day. But most scholars advocate that the minimum dose should not be less than 75mg per day. At present, most people take 25 ~ 40 mg every day, and the dose is too small. We believe that taking 75 ~ 100 mg orally every day can prevent arterial thrombosis; In order to prevent acute myocardial infarction or coronary heart disease after interventional therapy (such as stent implantation), 300 mg is taken orally, once a day/kloc-0. When do you take the medicine? Because of the long action time of aspirin, it is generally recommended to take 1 time every day. Taking it before breakfast often causes gastrointestinal discomfort, so most people choose to take it after breakfast. For the prevention of transient ischemic attack (TIA), 40mg/ time, twice a day, can be taken after breakfast and dinner. For patients with hypertension, it is best to take aspirin before going to bed, because the research shows that aspirin has synergistic antihypertensive effect, which can reduce systolic blood pressure by 7.0mmHg and diastolic blood pressure by 4.8mmHg on average. Therefore, taking aspirin at the same time can prevent cardiovascular events of mild to moderate hypertension and is beneficial to controlling hypertension before going to bed.