Introduction of estrogen replacement therapy

It has been introduced in the relevant items that the physiological and psychological changes of postmenopausal women are related to estrogen deficiency. In 1932, Esther and Spearman used estrogen preparation for the first time to prevent and treat menopausal syndrome. However, it was Rober Wilson in 1963 who realized for the first time that supplementing estrogen to postmenopausal women can not only treat various symptoms caused by menopause, but also delay and prevent the occurrence of menopause-related diseases. This method is called estrogen replacement therapy (ERT). Because progesterone is needed in most cases, it is also called hormone replacement therapy (HRT). More than 30 years of clinical practice and research have proved that,