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What are the advantages and disadvantages of systemic use of antibiotics to treat periodontitis?
(1) Drugs can reach the bottom of deep periodontal pocket and root bifurcation, which are difficult to reach, and help to sterilize here.
(2) It can kill microorganisms invading the periodontal pocket wall.
(3) It can remove pathogenic microorganisms in the non-periodontal pocket area of the oral cavity.
Disadvantages of systemic medication:
(1) After systemic administration, the drug concentration in periodontal pocket was relatively low.
(2) It is easy to induce drug-resistant strains.
(3) Large-dose and long-term use of antibacterial drugs can easily lead to flora imbalance.
(4) It is easy to produce adverse reactions, such as gastrointestinal reactions.
(5) It is difficult for some patients to adhere to the doctor's advice, which affects the curative effect.
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