What is the progress of COVID-19 vaccine research and development in various countries?

With the COVID-19 epidemic sweeping the world, the call for COVID-19 vaccine is getting stronger and stronger. At present, many countries and institutions have joined this vaccine research and development "competition". On February 29th, the World Health Organization released 3 1 candidate vaccines (including three mRNA vaccines) for COVID-19. At present, these vaccine research and development projects have made progress to varying degrees.

America 1

The National Institutes of Health of the United States issued a document in official website on June 16, saying that COVID-19 vaccine is undergoing clinical trials in Washington Institute of Health of Seattle Kaiser Medical Group. Forty-five volunteers will receive two arm muscle injections with an interval of about 28 days. They will be divided into three groups, with injection doses of 25 micrograms, 100 micrograms and 250 micrograms respectively, to evaluate the safety of different doses and their ability to induce human immune response.

Anthony Schmidt, director of NIAID, said that after a few weeks of vaccination, volunteers can obtain safety data through testing and they will be observed for one year. Even if the initial safety test of the vaccine goes well, it will take one to one and a half years before it can be put into large-scale application.

2. China

At 20: 65 on March 16, 2020,438+08, the recombinant COVID-19 vaccine developed by the scientific research team led by Academician Chen Wei of the Academy of Military Medical Sciences was approved to start clinical trials, but it still needs a lot of clinical trials before it can be put into use, and it will take half a year at the earliest.

3. Germany

On March 15, 2020, CureVac, a biopharmaceutical company headquartered in Tubingen, Germany, said that it is expected to develop an effective candidate vaccine for COVID-19 within a few months by using its vaccine development platform based on mRNA technology. During this period, the American and German governments attached great importance to the company's ability to quickly develop and produce vaccines, and competed for funds and secretly around the possible vaccine supply in the future.

Extended data:

Five R&D technical routes in China have been steadily advanced.

According to the recent news in the online edition of Forbes magazine, in addition to Moderna, there are Johnson & Johnson and Inovio in the United States.

Among them, Johnson & Johnson is re-adopting a new technology that has been successful in its Ebola and Zika vaccines, and the waiting time for the vaccine to go on the market is 8- 12 months; Inovio has just received $9 million from the Innovation Alliance for Epidemic Prevention and Control to develop the COVID-19 vaccine, which is expected to be tested in humans within seven months.

It is worth noting that after the outbreak of COVID-19, Chinese scientists quickly determined the whole genome sequence of COVID-19, and shared this information with the World Health Organization on June 5438+1October 65438+1October 0 1 day to help scientific research institutions around the world develop drugs.

At the press conference held on March 6th, Zheng Zhongwei, director of the Medical and Health Science and Technology Development Research Center of China National Health Commission, said that China is currently promoting vaccine research along five technical routes, including inactivated vaccine, recombinant subunit vaccine by genetic engineering, adenovirus vector vaccine, attenuated influenza virus vector vaccine and nucleic acid vaccine. On the whole, all five technical routes are progressing steadily.

Baidu Encyclopedia-novel coronavirus Vaccine

Public trust. An American COVID-19 vaccine entered clinical trials.