What are the traditional methods for testing biological materials? What are the advantages and disadvantages of the traditional methods of testing compared to the new methods?

Microbial traditional detection methods mainly refers to the traditional culture detection methods, classical PCR and other molecular detection methods, based on the antigen-antibody reaction of immunological detection methods and so on, a lot of these traditional detection methods are written into the national standard as a classic, in many aspects still have irreplaceable.

But it is undeniable that many of the traditional microbial detection methods are cumbersome, difficult to control the quality, time-consuming and laborious, and prone to subjective and one-sided errors.

With the advancement of science and technology, scientists have developed many new microbial detection methods, such as physical-based methods - odor fingerprinting technology, chemical-based methods - spectral fingerprinting technology, metabolic-based methods - chromatographic fingerprinting technology and other rapid detection methods. --chromatographic fingerprinting technology and other rapid non-destructive detection technology, microfluidic chip technology, CRISPR-based molecular detection technology.

These emerging detection methods are simple to operate, good accuracy, high sensitivity, rapid automated detection and analysis, greatly compensating for the shortcomings of the traditional microbial detection methods; the future direction of microbial detection development, or to combine the traditional detection methods and emerging detection methods complementary.