What is the principle that antibiotics harm liver and kidney?

1. the principle of liver injury caused by antibiotics

Fatty degeneration or necrosis of hepatocytes; Causing drug-induced hepatocellular hepatitis and drug-induced cholestasis hepatitis; Bilirubin excretion disorder leads to cholestasis and hepatitis. 2. The principle of kidney injury caused by antibiotics.

Causing renal tubular injury; Causing renal tubular obstruction; Lead to renal vasoconstriction, decreased renal blood flow and decreased renal function; Produce an immune response and cause interstitial nephritis.