What is the principle of COVID-19 vaccine? Do you think it's weird?

Introduction: At present, there are five kinds of vaccines in COVID-19, but the principle of research and development and production technology are different, so the principle of COVID-19 vaccine is also different. Inactivated vaccines, for example, mainly cultivate COVID-19 vaccine in vitro, and then inactivate the virus by physical methods, so that the virus does not have the ability to cause disease and reproduce, but can induce human immunity or antibodies to achieve the purpose of prevention. The recombinant protein vaccine mainly uses genetic engineering technology, takes novel coronavirus as antigen, produces protein in large quantities, and injects protein into human body to stimulate human body to produce antibodies. There is also a virus vector vaccine, which uses the modified virus as the carrier to induce immune response in human body. There are also nucleic acid vaccines, which are mainly divided into DNA and RNA by modern biotechnology. These two vaccines are absorbed by cells after entering the human body, and stimulate the human body to produce cellular immunity through a series of reactions to achieve the purpose of preventing diseases. Finally, attenuated vaccine is a kind of novel coronavirus for detoxification, which weakens the pathogenicity of the virus, retains the replication function of the virus and causes human immunity.

How does novel coronavirus spread the virus? If you want to enter the human body, you must first enter the cells of the human body and have the corresponding receptors of the virus. COVID-19's receptor is angiotensin in the body. This receptor exists in mucosal cells, and once the virus touches mucosal cells, it will lead to infection. There are many mucosal cells in human body, such as mouth, nasal cavity, eyelids, lips and so on. When the virus touches these places, it will cause infection. Once the virus enters cells, a series of reactions will occur, producing new virus particles and infecting more cells. When the virus is enough, it will spread to the trachea and reach the alveoli to cause pneumonia.

What symptoms will appear after COVID-19 is infected? After COVID-19 was infected, the incubation period was 4~ 14 days. Basically, many people are mild, and sometimes their illness may be more serious because of weak resistance. Generally, there will be symptoms such as fever, fatigue, dry cough and dyspnea, but some of them may not have fever. In severe cases, respiratory distress syndrome, shock and coagulation dysfunction will occur.

Finally, the most effective way to prevent COVID-19 vaccine is to vaccinate COVID-19 vaccine, which is free in China at present.