Pregnant women doing noninvasive DNA can test the fetus what

Every pregnant woman wants to give birth to a healthy baby during her pregnancy. Therefore, in order to be able to more clearly understand the physical condition of the fetus, mothers-to-be are very concerned about the pregnancy examination program. So, pregnant women do non-invasive DNA can inspect the fetus what ?

Pregnant women do non-invasive DNA can inspect the fetus what

Non-invasive prenatal genetic testing is through the collection of pregnant women peripheral blood (5 ml), the extraction of free DNA, the use of a new generation of high-throughput sequencing technology, combined with bioinformatic analysis, to derive the risk of the fetus suffering from chromosomal aneuploidy (21-trisomes also known as Down syndrome, 18-trisomes, 13-trisomes). The optimal time for this method is early or mid-pregnancy, and it is characterized by non-invasive sampling, no risk of miscarriage, high sensitivity, and high accuracy.

Studies have found that fetal free DNA can be detected in the peripheral blood of pregnant women starting at 4 weeks of gestation, and that the amount of fetal free DNA increases as the weeks of pregnancy increase. After 12 weeks of pregnancy, fetal free DNA can be extracted from the peripheral blood of the pregnant woman, and the new generation of gene sequencing technology combined with bioinformatics analysis can accurately determine whether the fetus has a chromosomal disorder.

Traditional serologic screening methods are based on the age, gestational week, hormone levels, and weight of the pregnant woman, which has a high false-positive rate and a high risk of missed tests.

Traditional prenatal diagnostics use invasive sampling methods, such as chorionic villus sampling, amniocentesis, and fetal umbilical vein puncture, which can confirm the presence of chromosomal aneuploidy, but the puncture wounds can lead to infections, and a certain number of miscarriages, among other risks.

In 1997, scientists discovered fetal free DNA fragments in the blood of pregnant women. Based on this discovery, non-invasive prenatal genetic testing was created. The technology only requires the collection of 5mL of pregnant women's venous blood, from which the free DNA originating from the plasma is extracted, and the new generation of high-throughput sequencing technology, combined with bioinformatic analysis, is used to derive the risk rate of chromosomal aneuploidy in the fetus.

Obstetric examination programs during pregnancy

The examination during pregnancy is mainly divided into three stages, early pregnancy, mid-pregnancy and late pregnancy, in these three stages will involve different examination programs.

In early pregnancy, that is, the first week of pregnancy - the 12th week, there are: ① ultrasound, it can rule out ectopic pregnancy, see the development of the fetus, measure the size of the fetus; ② check for pathogens that cause intrauterine infections, mainly to see whether they have been infected with the rubella virus, cytomegalic herpesvirus, toxoplasmosis protozoa, herpes simplex virus, etc.; ③ screening for hepatitis viruses, you can cut off the virus early The first step in the process is to check whether you are suffering from anemia, blood disorders, and urinary tract diseases.

In mid-pregnancy, that is, the 13th week of pregnancy - the 27th week, the main: ① color ultrasound in about 22 weeks of pregnancy, you can get a comprehensive understanding of the development of the fetus in the uterus, to rule out fetal abnormalities; ② in the 24-28 weeks of pregnancy, sugar screening, if the screening is positive, then we need to do a further test of glucose tolerance, in order to early detection of gestational diabetes and whether it is suffering from gestational diabetes; ② in the 24-28 weeks of pregnancy, glucose screening, if positive, then we need to do further test of glucose tolerance, in order to early detection of gestational diabetes and whether the Gestational diabetes mellitus; ③ 20 weeks of gestation should be MP measurement, predicting the tendency of gestational hypertension syndrome; ④ 16-20 weeks of gestation for Down syndrome (congenital anomalies) screening.

In late pregnancy, that is, the 28th week of pregnancy to production, the main: ① 32nd week to start fetal monitoring with fetal monitors, it is best to do the test once a week, you can observe and record the dynamic changes in fetal heart rate, but also predict the intrauterine reserve capacity of the fetus; ② Umbilical cord blood flow examination, you can detect the fetal umbilical cord resistance to blood flow, and understand whether there is intrauterine hypoxia; ③ ultrasound examination, you can The test can detect the resistance of fetal umbilical cord blood flow, and know whether there is intrauterine hypoxia; ③B ultrasound, can understand the maturity of the placenta, the amount of amniotic fluid and fetal growth and development; ④ in 36 weeks for blood type, coagulation quadruple test, kidney function, and review the liver function of the test, which is for the delivery of the preparations.

Highlights:

hCG Maternity Leave Blood Pressure Normal Range Down's Screening Amniotic Fluid Index Placental Maturity Maternity Insurance The Latest Labor Laws on Maternity Leave Best Time for Mid-Term Down's Screening