Research and development of key technologies for on-line detection of high purity citric acid fermentation process

With the wide application of citric acid, more and more enterprises began to incorporate it into their production plans. Fermentation is an indispensable link in citric acid production, and how to detect the key parameters of fermentation process online has become the research and development direction of producing high-purity citric acid.

At present, the key technologies of on-line detection of fermentation process mainly include the following aspects:

1. gas sensor technology: gas produced during fermentation is monitored by gas sensor, and the fermentation process and the growth state of bacteria are judged by analyzing the changes of gas concentration and flow rate.

2. Electrochemical technology: Through electrochemical experiments, the microbial metabolites in the solution, such as pH and oxygen concentration, can be detected by electrodes, which can realize real-time monitoring of the fermentation process.

3. Optical technology: quickly detect the content of metabolites in fermentation broth by spectral technology, such as mass spectrometry, Raman spectroscopy, infrared spectroscopy, etc.

4. Traditional analytical techniques: Traditional chemical analytical methods, such as titration and chromatography, are used to quantitatively analyze the components in fermentation broth, such as bacterial density and citric acid concentration.