Hepatitis B Core Antibody English

Hepatitis B core antibody, also known as anti-HBc, referred to as HBcAb. Including hepatitis B core antibody IgM and hepatitis B core antibody IgG which are common in competition law. After HBV infection, this antibody can be detected in the serum of most people, which is a sensitive serological marker.

It is also an early sign of acute infection of hepatitis B, which exists in serum for a long time, and some people have high titers. When HBsAg and anti -HBs are negative, hepatitis B core antibody can be detected from serum, and high titer of hepatitis B core antibody is also a sign of infection.

Anti-—HBc can be divided into three types: anti-—HBcIgM, anti-—HBcIgA and anti-—HBcIgG. These types appear and disappear in turn in HBV infection, and only IgG can exist for a long time. If only "anti-—HBc" is marked on the laboratory sheet without typing, it should be the sum of these three types, but most hospital laboratory sheets are IgM and IgG.

Anti-—HBclgM type, called "hepatitis B core antibody IgM type", is often suggested as acute HBV infection, or in the acute episode and active phase of chronic hepatitis B, with the extension of the course of disease or the improvement of the disease, IgM gradually disappears and is replaced by IgG.

Anti-HBcIgG type, called "hepatitis B core antibody IgG type", usually indicates chronic HBv infection or past infection. It used to be infected with hepatitis B virus, but now HBv has been eliminated, but IgG core antibody may still be detected in blood. This type of antibody exists in the blood of patients with chronic hepatitis B, and so does the convalescent patients with chronic hepatitis B.. The hepatitis B carriers we are talking about are all chronic hepatitis B carriers, and they should all be this kind of antibodies.

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