Traditional Culture Encyclopedia - Traditional stories - What is a monoclonal antibody drug
What is a monoclonal antibody drug
In 1975, British scientists Ketchel Milstein and George Koehler, fused antibody-producing B-lymphocytes with multiple myeloma cells to form hybrid tumor cells. These cells have the characteristics of both parents, the ability of myeloma cells to grow indefinitely and the antibody-producing function of B lymphocytes. As a result, these hybridoma cells are able to produce a large number of high-purity antibodies of a single type in cell culture. These antibodies are called "monoclonal antibodies". Monoclonal antibodies are significantly better than polyclonal antibodies in terms of specificity, potency, and preparation. The two scientists also won the 1984 Nobel Prize in Medicine and Physiology for their outstanding contribution to hybridoma technology.
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