What does liver biopsy mean? Why do you want to do a liver biopsy?

1 What is a liver biopsy? Clinically, liver biopsy has a history of 100 years. Liver biopsy is to take out the liver tissue about 1-2 cm long and as thin as a pin for light and electron microscopy, which is also called liver biopsy. With the continuous improvement of puncture instruments and operation methods, Montessori one-second liver puncture is widely used now, which is convenient and safe, with high success rate and no obvious adverse reactions, and has been widely used in clinic.

2. Assist in the diagnosis and differential diagnosis of various liver diseases. Many acute and chronic liver diseases that are difficult to diagnose in clinic, such as various viral hepatitis, alcoholic hepatitis, fatty liver, liver granuloma, liver tumor, liver abscess, liver tuberculosis, clinical trematode, primary biliary cirrhosis and various metabolic liver diseases (hepatolenticular degeneration, glycogen storage disease, liver amyloidosis), etc. You can know by liver puncture.

3. Provide etiological diagnosis of various types of viral hepatitis. Most hepatitis viruses are hepatotropic viruses, which are usually parasitic in liver tissues. At present, there are still some viral hepatitis, and it is difficult to determine its pathogen through clinical testing. Hepatitis virus parasitic in liver tissue can be detected by liver puncture, ultra-sensitive immunohistochemistry and in situ molecular hybridization.

4 Understand the degree and activity of liver lesions. Many patients with chronic hepatitis B have been infected with hepatitis B virus for a long time, but it may be half a year before blood tests find abnormal transaminase and the level of hepatitis B virus load is not high. Such patients can directly understand the pathological changes of liver tissue through liver biopsy, find out whether chronic liver disease is in active stage, infer the severity of its lesions, and make a more objective and accurate diagnosis.