How is Helicobacter pylori treated?

Question 1: How to treat Helicobacter pylori (HP positive+)? Once infected with Helicobacter pylori, it is difficult to completely eliminate it by antibiotic treatment, and most people will carry it for life. Helicobacter pylori mainly exists in the mouth and gastrointestinal tract, and many people don't know that they are infected. If you often feel stomachache (easy to attack when the season and climate change), abdominal distension, indigestion, bad breath, acid reflux, belching, etc. You are likely to be infected with Helicobacter pylori, so you should go to the hospital for Helicobacter pylori examination as soon as possible.

Dr. Xiao said that Helicobacter pylori is highly contagious. It enters the human body through infected food and water and "settles" and reproduces on the gastric mucosa, which first leads to gastritis and then develops into gastric ulcer and gastric cancer. Generally, it spreads through three ways: first, boiling the chopsticks for 10- 15 minutes every day can kill most of Helicobacter pylori; The second is to touch the shop. Helicobacter pylori infection can contaminate bedding and pillows through saliva and breath, causing infection among family members. They should always disinfect and replace bedding and pillows. Third, pets such as cats and dogs are easy to carry Helicobacter pylori, so close contact with pets should be avoided.

Drug treatment of helicobacter pylori infection, usually take 2~3 kinds of antibiotics and proton pump inhibitors, commonly known as triple therapy. However, it is easy to produce drug resistance of Helicobacter pylori, which brings side effects of destroying probiotics in digestive tract. Middle-aged and elderly friends can do three things well in their daily lives, which can also play a role in preventing and treating Helicobacter pylori. Cleaning the mouth is an important source of Helicobacter pylori infection. Taking metronidazole and other antibiotics for treatment generally kills Helicobacter pylori in the stomach, but it is often ineffective for the oral cavity, which is easy for bacteria in the oral cavity to enter the gastrointestinal tract and lead to repeated infections. Therefore, in order to prevent gastrointestinal infection, first of all, we must thoroughly remove Helicobacter pylori in the mouth.

There are also a large number of Helicobacter pylori in dental plaque. When the body's resistance drops, Helicobacter pylori swallowing with saliva or food will make waves, leading to stomach trouble. Helicobacter pylori in the mouth can also cause bad breath. To prevent and treat Helicobacter pylori, we must pay attention to oral cleaning, change the toothbrush every month, and insist on gargling and brushing your teeth after every meal to prevent plaque and plaque formation. In addition, a self-made medicinal toothpaste for killing Helicobacter pylori can be made. 20 grams of mint leaves (available in pharmacies) are ground into powder, 60 grams of toothpaste is extruded and put into a clean container. Adding peppermint powder, stirring evenly, and brushing your teeth every day for 30 days can effectively kill Helicobacter pylori parasitic on dental plaque.

Middle-aged and elderly friends who wear dentures should pay more attention to keeping their mouths clean. Before going to bed every night, you should take off your dentures and soak them in rice washing water. After getting up the next day, they should take them out, rinse them with a soft brush in clean water and put them in their mouths. Rice washing water contains a variety of biological enzymes, which has decontamination function and can avoid the formation of dental plaque, and rice washing water has no corrosive effect on dentures. Food disinfection

Cabbage has the function of antibiotics, which can kill many kinds of bacteria, including Helicobacter pylori. Drinking 1/4 chinese cabbage juice every day can relieve abdominal pain caused by gastric ulcer and duodenal ulcer after 3 weeks, which is helpful to the healing of two kinds of ulcer diseases. Cabbage also contains a chemical similar to gastrin ketone, which can secrete mucus from gastrointestinal cells to form a barrier, thus isolating it from gastric acid and protecting the stomach from harm. The fresher the cabbage, the better the anti-ulcer effect.

Purple garlic can inhibit the reproduction of Helicobacter pylori. Fresh garlic is spicy and has strong bactericidal power. Eat 1 purple garlic raw at dinner every day, and the antibacterial effect appears after two weeks.

When the experimental concentration of honey is 20 ~/6, it can inhibit all Helicobacter pylori. When the concentration is 10%, it can inhibit half of Helicobacter pylori. Honey mainly inhibits helicobacter pylori through osmosis; Therefore, honey should be drunk after meals to prolong its residence time in gastric mucosa. Put 30 ml of honey into a bowl, stir with chopsticks until it bubbles, add 120 ml of warm water, stir well, and then drink slowly.

Clove is a common Chinese herbal medicine, which has a strong anti-Helicobacter pylori effect. Drink 6 grams of cloves every day for two weeks.

Drinking tea with cold boiled water contains a lot of tea polyphenols, which has a strong effect on killing Helicobacter pylori. However, tea also contains caffeine, which will promote gastric acid secretion and is not good for gastrointestinal ulcers. Making tea with cold boiled water can reduce the dissolution of caffeine and will not secrete gastric acid. 5 grams of tea leaves are soaked in cold boiled water for half an hour before drinking.

Broccoli Fresh broccoli contains a lot of sulforaphane, which helps to fight Helicobacter pylori. The results showed that people who ate broccoli every day could reduce the level of Helicobacter pylori antigen in feces by more than 40%. Cut 200 grams of broccoli into small pieces, quickly scald it with boiling water, and cool it. Reduce gastric acid

Helicobacter pylori is suitable for >>

Question 2: How to treat Helicobacter pylori? At present, the following schemes are usually used to eradicate Helicobacter pylori:

1. Proton pump inhibitor (abbreviated as "PPI", such as omeprazole and lansoprazole)+two antibiotics: PPI mapping+amoxicillin 1.0g+ clarithromycin 0.5g twice a day, with 1 week as a course of treatment; PPI mapping+amoxicillin 1.0g+ metronidazole 0.4g twice a day, with 1 week as a course of treatment; PPI mapping+metronidazole 0.4g and clarithromycin 0.25g twice a day, 1 week is a course of treatment.

2. Bismuth: Livzon Triple: It is composed of bismuth (Livzon Dele) and two antibiotics, and it is a very effective drug to eradicate Helicobacter pylori at present. It can be taken in one course of treatment for seven days, and the radical cure rate is over 90%. Bismuth+two antibiotics: standard dose of bismuth (Livzondole is recommended)+amoxicillin 0.5g+ metronidazole 0.4g, twice a day, 2 weeks for 1 course of treatment; Standard dose of bismuth (recommended for Livzon)+tetracycline 0.5g+ metronidazole 0.4g, twice a day, 2 weeks for 1 course of treatment; Standard dose of bismuth (recommended to use Livzon)+clarithromycin 0.25g+ metronidazole 0.4g, twice a day, 2 weeks for 1 course of treatment.

3. Other schemes: Ranitidine Bismuth Citrate (RBC)0.4g replaces PPI in the recommended scheme 1. H2 receptor antagonist H2-RA) or PPI+ recommended scheme 2 constitute quadruple therapy, with one week as a course of treatment. Metronidazole 0.4g can be replaced by tinidazole 0.5g. ..

It is necessary to prevent Helicobacter pylori infection. Pay attention to personal hygiene: such as gargling after each meal, eating separately, cleaning vegetables and fruits, etc. To minimize the chance of infection.

Question 3: How does Helicobacter pylori cure Helicobacter pylori infection with drugs? Usually take two or three antibiotics and proton pump inhibitors, commonly known as triple therapy. However, it is easy to produce drug resistance of Helicobacter pylori, which brings side effects of destroying probiotics in digestive tract. Middle-aged and elderly friends can do three things well in their daily lives, which can also play a role in preventing and treating Helicobacter pylori. Cleaning the mouth is an important source of Helicobacter pylori infection. Taking metronidazole and other antibiotics for treatment generally kills Helicobacter pylori in the stomach, but it is often ineffective for the oral cavity, which is easy for bacteria in the oral cavity to enter the gastrointestinal tract and lead to repeated infections. Therefore, in order to prevent gastrointestinal infection, first of all, we must thoroughly remove Helicobacter pylori in the mouth.

Question 4: Has Helicobacter pylori been completely eradicated in my body? Disease analysis:

Helicobacter pylori is only one of the normal flora in human body, and it is impossible to completely eradicate it. Under normal circumstances, it is not pathogenic.

Guiding opinions:

Generally, after 1 to 2 weeks of regular anti-Helicobacter pylori treatment, most infected people can be cured. Helicobacter pylori infection can be cured. The general principle of treatment is mainly antibiotics. Radical treatment is also recommended for patients with chronic atrophic gastritis, dyspeptic symptoms with poor curative effect after conventional treatment, patients with reflux esophagitis who need long-term acid suppression treatment and patients who need to take non-steroidal anti-inflammatory and analgesic drugs for a long time. Those who do not meet these conditions will be selected by the doctor after explaining the advantages and disadvantages in detail.

Life care:

Spicy hard food, hard food, moldy food, coffee, barbecue, hot pot, tobacco and alcohol are forbidden. This disease focuses on maintenance, and the cure of gastric ulcer needs a difficult and lasting process. In addition to cooperating with medical staff to do self-care, patients mainly follow the guiding ideology of "three-point treatment and seven-point nutrition" of traditional Chinese medicine for gastrointestinal diseases.

Hello! As long as the treatment is correct, it can be cured. Helicobacter pylori (HP) is an important cause of gastric diseases, and general conventional treatment methods are difficult to work, which can only alleviate the disease, can not solve the fundamental problem, and are easy to repeat. Traditional Chinese medicine in the motherland has a very unique treatment method, so it is recommended that you use traditional Chinese medicine such as black alum, black dates, walnut kernels, gardenia, angelica, Amomum villosum, magnolia officinalis, sparganium, pangolin scales, inchqu, malt and onychomycosis. These traditional Chinese medicines have a unique formula, which can directly attack the focus, completely eliminate Helicobacter pylori, increase the gastric mucosal barrier and eliminate the root cause, thus achieving the goal of complete cure.

You can buy these medicines at the local drugstore. I hope you can get the right treatment and get well soon!

Hello, Helicobacter pylori is the main cause of gastritis, and the eradication rate is 78%. Thank you.

Disease analysis:

Drugs that can treat Helicobacter pylori can be selected for treatment.

Guiding opinions:

It can be completely cured ~ but you won't get an immune body. If you eat with people with helicobacter pylori, you will still be infected with helicobacter pylori.

Disease analysis:

Helicobacter pylori is a kind of unipolar, flagellate, blunt-ended, spirally curved bacteria. It is 2.5 ~ 4.0 microns long and 0.5 ~ 1.0 microns wide. Gram staining is negative and dynamic. It often appears on the surface of gastric mucosal epithelial cells in a typical spiral or arc shape. When it grows on a solid medium, it sometimes takes the form of a rod or a ball.

Under normal circumstances, the stomach wall has a series of perfect self-protection mechanisms (gastric acid, secretion of protease, protection of insoluble and soluble mucus layer, regular exercise, etc.). ) can resist the invasion of thousands of microorganisms through the mouth. Since the discovery of Helicobacter pylori on the surface of gastric mucosal epithelial cells, I realized that Helicobacter pylori is almost the only culprit that can break through this natural barrier. Helicobacter pylori infection significantly increases the risk of duodenal ulcer and gastric ulcer. About 65,438+0/6 people infected with Helicobacter pylori may develop peptic ulcer disease. Treating Helicobacter pylori infection can accelerate ulcer healing and greatly reduce the recurrence rate of ulcer. Only using anti-Helicobacter pylori drugs without acid inhibitors shows that gastric and duodenal ulcers can also be effectively cured. Helicobacter pylori infection is related to some diseases that cause gastric and duodenal ulcers.

Guiding opinions:

The selection principle of treatment scheme: ① combined medication; ② The eradication rate of Helicobacter pylori is over 80%, preferably over 90%; ③ No obvious side effects, and the patient is well tolerated; ④ The patient's economic endurance. The therapeutic effect of Helicobacter pylori infection should be judged by the eradication rate of Helicobacter pylori, not the clearance rate. Eradication means that at least one month after the termination of treatment, bacteriology, histopathology or isotope tracing confirm that there is no bacterial growth.

You should pay attention to oral hygiene before eradicating Helicobacter pylori. You can replace the dental appliance and use mouthwash and antibacterial toothpaste for a period of time to repair oral problems such as tooth decay, dental calculus and dental calculus.

At present, the commonly used anti-Helicobacter pylori drugs at home and abroad include amoxicillin, metronidazole, clarithromycin, tetracycline, doxycycline, furazolidone, organic colloidal bismuth (de-nol) and so on. ), Vitello tablets (Suweile), Lewei, Pi's powder and Pingping. Patients with peptic ulcer can properly use proton pump inhibitors or h2 receptor antagonists in combination with two antibiotics or proton pump inhibitors (such as omeprazole). & gt

Question 5: How to treat Helicobacter pylori infection is mainly anti-Helicobacter pylori drug treatment.

Although Helicobacter pylori is sensitive to many antibacterial drugs in vitro, it is not so satisfactory to use drugs in vivo. This is because Helicobacter pylori is mainly parasitic in mucus.

prospecting instrument

Below the layer, on the surface of gastric epithelial cells. Injection has no effect on it, and the oral effect is greatly limited by the gastric acid environment, the barrier of mucus layer and the continuous emptying of the stomach. In addition, some drugs are prone to serious side effects or drug-resistant strains after long-term application. Therefore, diseases such as acute and chronic gastritis and peptic ulcer caused by Helicobacter pylori infection seem to be easy to treat, but they are not always effective. What's more, there is no suitable animal model of Helicobacter pylori infection at present, which can help to formulate effective treatment plans.

Therefore, the current treatment schemes are almost all based on clinical experience and have great limitations (due to differences between regions and populations). Generally speaking, it is not recommended to use a single antibacterial drug at present, because its cure rate is low, generally 80%, preferably above 90%;

③ No obvious side effects, and the patient is well tolerated;

④ The patient's economic endurance.

The curative effect of Helicobacter pylori infection should be judged by the eradication rate of Helicobacter pylori, not the clearance rate. Eradication means that at least one month after the termination of treatment, bacteriology, histopathology or isotope tracing confirm that there is no bacterial growth.

At present, the commonly used anti-Helicobacter pylori drugs at home and abroad are: Weifuchun tablets, amoxicillin, metronidazole, clarithromycin, tetracycline, doxycycline, furazolidone, organic colloidal bismuth (de-nol) and so on. ), vitale tablets (Su Weile), Le Wei, Pi Shi San Heping. Patients with peptic ulcer can be properly combined with proton pump inhibitor or h2 receptor antagonist plus two antibiotics, or proton pump inhibitor (such as omeprazole) plus one antibiotic.

Drug treatment plan:

Omeprazole (pantoprazole or rabeprazole)+clarithromycin (levofloxacin)+amoxicillin (metronidazole)

Treatment time: the course of treatment is generally two weeks. Due to the wide application of antibacterial schemes for the treatment of Helicobacter pylori infection, it is possible to expand the problem of drug resistance. Therefore, the research of alternative treatment or preventive strategies, such as vaccine prevention or immunotherapy, is a problem worthy of attention in the future.

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Preventive strategies:

Pay attention to oral hygiene before eradicating helicobacter pylori. Use mouthwash and antibacterial toothpaste for a period of time to repair oral problems such as tooth decay, tartar and calculus. You can change your braces first. Dental appliances should not be placed in the bathroom, but should be placed where the sun can shine. Bathrooms without windows should be disinfected regularly with ultraviolet rays for more than 30 minutes. Mouth cups, water cups and stainless steel thermos cups should not be mixed, and they should be cooked and disinfected frequently, especially during detoxification.

1, change the toothbrush, disinfect the patient's cup washing utensils on time, and use mouthwash in the morning and evening. Mouthwash should have bactericidal effect, that is, its formula is a chemical agent, such as domiphen, thymol or compound tinidazole solution. Chinese herbal mouthwash is ineffective.

2, infectious and highly contagious, when someone is infected at home, be sure to eat separately, and disinfect the tableware with a household disinfection cabinet after every meal every day.

3. Because most patients didn't do it in the first step, that is, they didn't use medical mouthwash, didn't disinfect personal washing utensils, and just blindly took the "triple medicine". Such treatment will only improve temporarily, and the recurrence rate is high after stopping the drug. It will not fully recover in a year or two or even longer, and eventually develop into gastritis or atrophic gastritis. Patients who complete the first step will recover in less than two weeks.

It is best to take antacids on an empty stomach before going to bed. Choose one of omeprazole, rabeprazole and lansoprazole.

5. Be sure to use antibacterial drugs, and don't eat sour food or drink yogurt during medication, otherwise the treatment will be in vain.

6, Helicobacter pylori drug resistance treatment

Proton pump inhibitor or h2 receptor antagonist+bismuth+amoxicillin+levofloxacin 10- 14 days, or proton pump inhibitor or h2 receptor antagonist+bismuth+amoxicillin+levofloxacin for 5-7 days, followed by proton pump inhibitor or h2 receptor antagonist+bismuth+amoxicillin+levofloxacin for 5-7 days. The eradication rate of Helicobacter pylori can reach about 90%. ...& gt& gt

Question 6: How to treat Helicobacter pylori infection? Brief introduction of triple therapy:

Gastric triple therapy refers to colloidal bismuth or proton pump inhibitor (PPI)+ two antibiotics. Generally speaking, the time of triple therapy is one to two weeks. In addition, gastric mucosal protective agents, drugs to promote gastric emptying, anticholinergic drugs, etc. It can be used appropriately according to the condition.

Advantages of triple therapy:

Compared with single antibiotic therapy and dual therapy, triple therapy has the advantage of high eradication rate. A few years ago, when the drug resistance of Helicobacter pylori was not so common now, the eradication rate of triple therapy could reach 85%-95%.

Problems of triple therapy:

The first is the problem of side effects. Almost all commonly used antibiotics have some side effects. For example, metronidazole, the two most commonly used antibiotics in Sanlian, can cause nausea and burr on the tip of the tongue; Amoxicillin and erythromycin can cause diarrhea, nausea, glossitis, allergic urticaria, rash and drug fever.

Then, the most important problem that puzzles clinicians in recent years is the increase of drug resistance of Helicobacter pylori. According to the data released recently by the 6th Clinical Diagnosis and Treatment Forum of Helicobacter pylori, due to the improvement of drug resistance, the eradication rate of traditional triple Helicobacter pylori is decreasing year by year. At present, the triple eradication rate in some areas has dropped to about 65%.

Quadruple therapy of helicobacter pylori

Brief introduction of quadruple therapy:

Quadruple therapy refers to the treatment scheme of colloidal bismuth plus three antibiotics. Commonly used drug combinations and dosages are as follows:

1, potassium bismuth citrate 240mg+ amoxicillin 750mg+ metronidazole 400mg+ omeprazole 20mg.

2. Potassium bismuth citrate 240mg+ erythromycin 500mg+ metronidazole 400mg+ omeprazole 20mg.

3, bismuth potassium citrate 240mg+ tetracycline 500mg+ metronidazole 400mg+ omeprazole 20 mg.

7 ~ 14 days is a course of treatment. After a course of treatment, potassium bismuth citrate should be taken alone for 6 weeks, with the same dosage and usage as before. Pay attention to the skin test of amoxicillin (amoxicillin is a broad-spectrum antibiotic of penicillin. )

Advantages of quadruple therapy:

The remission rate and eradication rate of quadruple therapy for Helicobacter pylori infection are higher than that of triple therapy, in which the remission rate is more than ten percentage points higher and the eradication rate is several percentage points higher. The drug resistance rate of quadruple therapy is slightly lower than that of triple therapy, which is the most commonly used first-line treatment scheme for Helicobacter pylori and the second-line treatment scheme after the failure of triple therapy.

Problems of quadruple therapy:

Due to the addition of an antibiotic, the remission rate and eradication rate of quadruple therapy are not only higher than that of triple therapy, but also the incidence of side effects is 5 percentage points higher than that of triple therapy, which is about 30%. Although the drug resistance rate is temporarily lower than that of Sanlian, it is also getting higher and higher. Therefore, the eradication rate of Helicobacter pylori in quadruple therapy is also decreasing year by year. According to the latest data, the eradication rate of quadruple therapy has dropped to about 70%.

Research progress of quadruple therapy;

Like triple therapy, the latest research shows that the eradication rate of quadruple can be improved if the antibiotics with low drug resistance such as furazolidone are used instead of the antibiotics with high drug resistance such as metronidazole. In addition, the study also shows that extending the course of quadruple therapy can also improve the eradication rate of Helicobacter pylori.

Probiotic therapy of helicobacter pylori

With the eradication rate of triple and quadruple Helicobacter pylori decreasing year by year, the sixth national clinical forum on Helicobacter pylori infection and digestive system diseases and the round table meeting on the new path of Helicobacter pylori treatment have been widely concerned and recognized.

Du Yiqi, Hu Fulian and other experts introduced the probiotic therapy of Helicobacter pylori in detail:

Brief introduction of probiotic therapy:

Probiotic therapy refers to the method of adding probiotic preparation on the basis of traditional triple or quadruple, or directly using Viacom probiotic preparation to eradicate Helicobacter pylori.

Advantages of probiotic therapy:

At present, clinical studies at home and abroad show that probiotic therapy can improve the eradication rate of triple and quadruple 10-20% and reduce the adverse reactions of triple and quadruple by more than 20%.

Problems of probiotic therapy:

At present, the main question is whether probiotics are triple or quadruple combination or single use is better, which remains to be verified.

Nursing care of Helicobacter pylori after rehabilitation

1. If you want to change your diet, you should choose a separate dining system or use public chopsticks.

Don't drink boiled water, don't eat cooked food raw, and drink sterilized milk.

3. Experiments have proved that patients with peptic ulcer are also in danger of spreading diseases by kissing people, so we should be vigilant.

4. Develop good hygiene habits and wash your hands before and after meals. Tableware used frequently must also be strictly disinfected.

5. Don't put cleaning supplies such as dental appliances in hygiene ... >>