Is cod liver oil emulsion water-in-oil or oil-in-water

Oil in water. The traditional three-dimensional cod liver oil emulsion is an oil-in-water emulsifier, that is, o/w emulsion. Its main components contain fat-soluble vitamins A, D and water-soluble vitamin C. Vitamin C is soluble in the water phase of emulsion, which is very unstable and easily degraded in water. The following two methods are mostly used to solve the problem of instability of vitamin C in aqueous solution: First, refer to the production method of vitamin C injection, and the whole production process should be carried out in an oxygen-free environment. Adding chelating agent, antioxidant and other auxiliary materials. Because the three-dimensional cod liver oil emulsion is an oral emulsion and packaged in multiple doses, it is difficult to be oxygen-free in the whole process of processing and preparation. This strictly controlled process can only alleviate the degradation of vitamin C, but can not completely solve the degradation problem. Secondly, vitamin C was made into inclusion compounds and liposomes, which were applied to solid preparations and semi-solid preparations. This inclusion compound is not suitable for emulsion.