What is the principle of aggregation-induced luminescence (AIE)

In dilute solution, there is active vibration and rotation inside AIE molecules. When these molecules absorb energy, all kinds of vibrations and rotations "sit on the floor and divide the energy", so they emit less light.

However, when these molecules gather together, the mutual restraint limits the internal movement of the molecules, and the "uneven distribution of spoils" of energy by various vibrations and rotations makes them not benefit, but gain more energy through luminescence, thus showing the phenomenon of enhanced luminescence. ?

Since the discovery of aggregation-induced luminescence (AIE), the team of Academician Tang Benzhong began to look for AIE materials which are completely opposite to luminescence quenching, developed many AIE systems, and realized the application of AIE materials in photoelectric devices, intelligent materials, chemical sensing, biological sensing and imaging.

Summary of conclusion

Aggregation-induced luminescence (AIE) materials have the advantages of durability, strong resistance to photobleaching and elution, and are widely used in cell and tissue imaging. Biological imaging requires light to have little damage to the living body and strong penetration, so red/near-infrared AIE material is preferred. On the basis of insisting on developing the new AIE material system, this topic takes the above-mentioned actual needs as the core content, and after four years of research, it has achieved a series of results.

AIE with tetraethylene (TPE) as chromophore, red-red AIE molecule TPE-IND with 2- hydroxyindole and TPE * * and red-red AIE material TPE-TCF；; Developed by D-A structural design company. The solid-state emission peak of TPE-TCF is 660nm, and the efficiency is 24. 8%。

Refer to the above content: Baidu Encyclopedia -AIE red nanomaterials are used for biological detection and imaging.